In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). In-hospital outcomes were compared in patients with high and low DFR values. With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p < 0.001). The length of ICU stay was longer in the third tertile group (p < 0.001). When evaluated together with infection markers, DFR was found to be an independent predictor of outcomes. DFR can be used as a prognostic marker in patients with COVID-19 with a diagnosis of HF, and perhaps more valuable than other infection markers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547277 | PMC |
| http://dx.doi.org/10.2217/bmm-2021-0341 | DOI Listing |
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