Telavancin, a lipoglycopeptide antibiotic, is traditionally dosed at 10 mg/kg based on total body weight but is associated with toxicities that limit its use. This study supports the use of a capped dosing regimen of 750 mg in obese patients, which is associated with equal efficacy and fewer adverse effects compared to traditional dosing.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765302PMC
http://dx.doi.org/10.1128/AAC.01603-21DOI Listing

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