Background: Although the long-term success rate of dental implants is currently close to 95%, it is necessary to provide more evidence on the factors related to the failure of osseointegration and survival.
Purpose: To establish the risk factors associated with the failure of osseointegration and survival of dental implants with an internal connection and machined collar and to establish a predictive statistical model.
Materials And Methods: An analytical, retrospective, and observational clinical study of a sample of 297 implants with a follow-up of up to 76 months. Independent variables related to the implant, patient, and surgical and rehabilitative procedures were identified. The dependent variables were failure of osseointegration and failure of implant survival after prosthetic loading. A survival analysis was carried out by applying the Kaplan-Meier model (significance for < 0.05). The log-rank test and the Cox regression analysis were applied to the factors that presented differences. Finally, the regression logit function was used to determine whether it is possible to predict the risk of implant failure according to the analyzed variables with the data obtained in this study.
Results: The percentages of osseointegration and survival were 97.6 and 97.2%, respectively. For osseointegration, there were significant differences according to gender ( = 0.048), and the risk of nonosseointegration was 85% lower in women. Regarding survival, the Cox analysis converged on only two factors, which were smoking and treatment with anticoagulant drugs. The risk of loss was multiplied by 18.3 for patients smoking more than 10 cigarettes per day and by 28.2 for patients treated with anticoagulants.
Conclusions: The indicated risk factors should be considered, but the analysis of the results is not sufficient to create a predictive model.
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http://dx.doi.org/10.1155/2021/9684511 | DOI Listing |
J Oral Implantol
December 2024
School of Dentistry, Section of Periodontics, University of California, Los Angeles, Los Angeles, California, United States.
Unlabelled: Peri-implantitis (PI) is an inflammatory disease that affects supportive tissues around dental implants, and its progression eventually leads to bone loss and implant failure. However, PI effects may be different based on the presence or absence of adjacent teeth.
Objective: To investigate the differences in bone loss and inflammation between implants placed adjacent to a tooth or edentulous area in a ligature-induced PI model.
Biomater Res
December 2024
Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China.
Despite that the clinical application of titanium-based implants has achieved great success, patients' own diseases and/or unhealthy lifestyle habits often lead to implant failure. Many studies have been carried out to modify titanium implants to promote osseointegration and implant success. Recent studies showed that exosomes, proactively secreted extracellular vesicles by mammalian cells, could selectively target and modulate the functions of recipient cells such as macrophages, nerve cells, endothelial cells, and bone marrow mesenchymal stem cells that are closely involved in implant osseointegration.
View Article and Find Full Text PDFAdv Healthc Mater
December 2024
School of Chemical Engineering, University of Birmingham, Birmingham, B15 2TT, UK.
Current biomedical titanium alloys have been repurposed from other industries, which has contributed to several biologically driven implant failure mechanisms. This review highlights the added value that may be gained by building an appreciation of implant biological responses at the onset of alloy design. Specifically, the fundamental mechanisms associated with immune response, angiogenesis, osseointegration and the potential threat of infection are discussed, including how elemental selection can modulate these pivotal systems.
View Article and Find Full Text PDFJ Long Term Eff Med Implants
December 2024
Branemark Osseointegration Center, Vijaynagar, Bengaluru 560040, India.
The "all-on-four" treatment modality is a treatment in which four implants are surgically placed in the completely edentulous jaw in order to restore immediately loaded implant supported fixed restoration. The aim of the present study was to compare clinical, radiological and prosthetic outcomes of immediately loaded maxillary and mandibular four implant supported cross-arch fixed denture prosthesis. A total of 112 edentulous patients who were rehabilitated for their complete maxillary and mandibular edentulism using All-on-four concept between January 2010 to August 2012 in four private dental clinics were included in this study for retrieve their data for marginal bone loss, implant survival rate, and prosthetic complication for a period of 8 years of follow-up.
View Article and Find Full Text PDFDent Med Probl
December 2024
Department of Prosthetic Dentistry and Gerodontology, Poznan University of Medical Sciences, Poland.
Background: Ceramic endosseous implant coatings have gained esteem due to their favorable osteoinductive and osteoconductive properties. However, such a layer may be prone to failure under in vivo conditions, which necessitates its modification.
Objectives: The aim of the present study was to modify an electrodeposited hydroxyapatite (HA) coating on titanium (Ti) with ultrashort-pulsed lasers for the incorporation of the ceramic into the sample surface and the texturing of the metal surface.
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