AI Article Synopsis
- Healthcare workers (HCWs) are at high risk for contracting SARS-CoV-2, and studying their antibody seroprevalence can reveal important insights into their exposure and infection control practices.
- A study assessed SARS-CoV-2 antibody levels among HCWs, categorizing participants into high-risk and low-risk groups, and tested for IgG and IgM antibodies using rapid tests.
- Results showed a low overall seroprevalence (3.9%), with higher rates among high-risk HCWs and those with COVID-19 symptoms, suggesting effective infection control but highlighting the need for stricter measures in dedicated COVID wards.
Article Abstract
Statement Of The Problem: Healthcare workers (HCW) are the most vulnerable group for contracting SARS-CoV-2. Assessment of seroprevalence of SARS-CoV-2 antibodies among HCW, thus can provide important data on pathogen exposure, infectivity, and adherence to personal protective equipment (PPE). The present study aimed at assessing SARS-CoV-2 seroprevalence among HCW and exploring associations with demographics, category of exposure to COVID-19 patients, preventive measures taken and relation with COVID-19 symptoms.
Method Of Study: HCWs with a minimum gap 2 weeks from last duty were eligible to participate in the study. The enrolled HCW were categorized into high-risk and low-risk category based on work in COVID-19 areas. HCWs SARS-CoV-2 specific IgG and IgM antibodies were detected using rapid immunochromatography test.
Results: Out of 821 randomly selected HCWs, either IgM or IgG antibody was detected in 32 HCWs (32/821, 3.9%). Only IgM antibodies were detected in 14 (1.7%), only IgG was detected in 9 (1.0%), and both IgM and IgG antibodies were present in 9 HCWs. Seropositivity was significantly higher in high-risk category (5.7% vs. 2.2.%), HCWs who ever had COVID-19 related symptoms in last 3 months (5.6% vs. 2.8%), and those who had earlier tested positive for SARS-CoV-2 with real-time reverse transcriptase PCR (36.6% vs. 3.5%). Seroprevalence was highest (6.9%) among housekeeping and sanitation staff.
Conclusions: Overall, low seroprevalence of SARS-CoV-2 antibodies in our HCWs is an indicator of effective infection control practice. HCW posted in dedicated COVID ward need more stringent implementation of infection prevention measures.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483124 | PMC |
| http://dx.doi.org/10.4103/jfmpc.jfmpc_2486_20 | DOI Listing |
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