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A comprehensive insights of cancer immunotherapy resistance.
Med Oncol
January 2025
Department of In Vivo Pharmacology, TCG Lifesciences Pvt. Ltd, BN 7, Sector V, Salt Lake City, Kolkata, West Bengal, 700091, India.
Cancer is a major global health issue that is usually treated with multiple therapies, such as chemotherapy and targeted therapies like immunotherapy. Immunotherapy is a new and alternative approach to treating various types of cancer that are difficult to treat with other methods. Although immune checkpoint inhibitors have shown promise for long-term efficacy, they have limited effectiveness in common cancer types such as breast, prostate, and lung.
View Article and Find Full Text PDF[Nosocomial gastrointestinal infections and Clostridioides difficile].
Dtsch Med Wochenschr
February 2025
German surveillance data from 2022 reported a prevalence of nosocomial infections among hospitalized patients of 5,2%. Clostridioides-difficile-infections (CDI) are the most frequent cause of nosocomial diarrhea. They are usually caused by antibiotic exposure and the subsequent changes in the gut microbiota.
View Article and Find Full Text PDFPrecise morphology control of all-organic core-shell droplets for synthesis of microencapsulated phase change materials through AC electric fields.
J Colloid Interface Sci
January 2025
National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics, Research Institute of Aero-Engine, Beihang University, Beijing 100191, China. Electronic address:
Hypothesis: Complex emulsions usually consist of aqueous phases, like oil-in-water-in-oil (o/w/o) and water-in-oil-in-water (w/o/w), serving foundational roles in colloid science. Oil-in-oil-oil (o/o/o) emulsions offer new avenues for non-aqueous reagents but face challenges in balancing the forces between multiple organic phases.
Experiments: In this work, we generate o/o/o emulsions by integrating an AC electric field with a double cross-junction microchannel.
[Trigeminal neuralgia - Overview].
Laeknabladid
February 2025
Department of Neurology, University Hospital of Iceland, Reykjavik, Iceland.
Trigeminal neuralgia is the most common cause of facial pain in individuals over 50 years old and can have a profoundly negative impact on quality of life. Epidemiological studies have measured the annual incidence of trigeminal neuralgia at around 4-5 cases per 100,000 inhabitants per year. In Iceland, this would amount to about 16-20 new cases annually.
View Article and Find Full Text PDFCoherent lensless imaging usually suffers from coherent noise and twin-image artifacts. In the terahertz (THz) range, where wavelengths are 2 to 4 orders of magnitude longer than those in the visible spectrum, the coherent noise manifests primarily as parasitic interference fringes and edge diffraction, rather than speckle noise. In this work, to suppress the Fabry-Pérot (F-P) interference fringes, we propose a novel method, which involves the averaging over multiple diffraction patterns that are acquired at equal intervals within a sample's half-wavelength axial shift.
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