This study aimed to examine sex differences in oxygen saturation in respiratory (SmO-) and locomotor muscles (SmO-) while performing physical exercise. Twenty-five (12 women) healthy and physically active participants were evaluated during an incremental test with a cycle ergometer, while ventilatory variables [lung ventilation ( E), tidal volume (Vt), and respiratory rate (RR)] were acquired through the breath-by-breath method. SmO was acquired using the MOXY devices on the and . A two-way ANOVA (sex × time) indicated that women showed a greater significant decrease of SmO-, and men showed a greater significant decrease of SmO-. Additionally, women reached a higher level of ΔSmO- normalized to E (L⋅min) ( < 0.001), whereas men had a higher level of ΔSmO- normalized to peak workload-to-weight (watts⋅kg, PtW) ( = 0.049), as confirmed by Student's -test. During an incremental physical exercise, women experienced a greater cost of breathing, reflected by greater deoxygenation of the respiratory muscles, whereas men had a higher peripheral load, indicated by greater deoxygenation of the locomotor muscles.
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http://dx.doi.org/10.3389/fphys.2021.738063 | DOI Listing |
Biomimetics (Basel)
January 2025
Center for Interdisciplinary Research in Rehabilitation and Social Integration, Centre Intégré Universitaire de Santé et de Services Sociaux de la Capitale-Nationale, Quebec, QC G1C 3S2, Canada.
Exoskeletons are used in rehabilitation centers for people with spinal cord injuries (SCI) due to the potential benefits they offer for locomotor rehabilitation. The acceptability of exoskeletons is crucial to promote rehabilitation and to ensure a successful implementation of this technology. The objective was to explore the acceptability of overground wearable powered exoskeleton used in rehabilitation among people with SCI.
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Hepato-Neuro Laboratory, Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, 900, Rue Saint-Denis - Pavillon R, R08.422, Montréal (Québec), H2X 0A9, Canada.
Sarcopenia and hepatic encephalopathy (HE) are complications of chronic liver disease (CLD), which negatively impact clinical outcomes. Hyperammonemia is considered to be the central component in the pathogenesis of HE, however ammonia's toxic effects have also been shown to impinge on extracerebral organs including the muscle. Our aim was to investigate the effect of attenuating hyperammonemia with ornithine phenylacetate (OP) on muscle mass loss and associated molecular mechanisms in rats with CLD.
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National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing, China.
Skeletal muscle (SKM) has crucial roles in locomotor activity and posture within the body and also functions have been recognized as an actively secretory organ. Numerous bioactive molecules are secreted by SKM and transported by extracellular vesicles (EVs), a novel class of mediators of communication between cells and organs that contain various types of cargo molecules including lipids, proteins and nucleic acids. SKM-derived EVs (SKM-EVs) are intercellular communicators with significant roles in the crosstalk between SKM and other organs.
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Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Exogenous neural stem cells (NSCs) have great potential to reconstitute damage spinal neural circuitry. However, regulating the metabolic reprogramming of NSCs for reliable nerve regeneration has been challenging. This report discusses the biomimetic dextral hydrogel (DH) with right-handed nanofibers that specifically reprograms the lipid metabolism of NSCs, promoting their neural differentiation and rapid regeneration of damaged axons.
View Article and Find Full Text PDFProc Biol Sci
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Department of Anatomy, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY 11568, USA.
Powerful digital grasping is essential for primates navigating arboreal environments and is often regarded as a defining characteristic of the order. However, data on primate grip strength are limited. In this study, we collected grasping data from the hands and feet of eleven strepsirrhine species to assess how ecomorphological variables-such as autopodial shape, laterality, body mass and locomotor mode-influence grasping performance.
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