Ecthyma gangrenosum as a serious complication of infection in departments of paediatric oncology.

Postepy Dermatol Alergol

Faculty of Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.

Published: August 2021

In most cases is a consequence of bloodstream infection in immunodeficient patients. This bacterium is characterized by multi-drug resistance and has a number of mechanisms that allow it to survive even in extreme conditions. The disease is characterized by an aggressive course involving the skin and mucous membranes, leading to ulceration with signs of necrosis within 12 to 24 h. Treatment includes targeted antibiotic therapy and surgical cleansing of the wound. If the perianal area is occupied, a colostomy may be performed. Prevention of bacterial infections involves taking special precautions when handling a patient with immunodeficiency.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501443PMC
http://dx.doi.org/10.5114/ada.2020.100747DOI Listing

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