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A retrospective review of the common childhood illnesses and the indications for antibiotic prescription at community hospital in Malawi.
Front Antibiot
September 2024
Research and Education, Clinical Research Education and Management Services (CREAMS), Lilongwe, Malawi.
Background: Childhood remains a vulnerable period and a key determiner for adult health. Various illnesses experienced by children in their early years determine future performance and contribution to society. Acute and chronic infectious diseases, undernutrition, and early childhood non-communicable diseases have greatly been linked to intellectual disability, poor childhood development, increased morbidity, and household and healthcare economic costs.
View Article and Find Full Text PDFDeep Neck Infections. Review of 111 cases.
Otolaryngol Pol
January 2025
Riga Paul Stradins University, Riga, Latvia.
<b>Introduction:</b> Deep neck infections (DNI) are potentially life-threatening conditions. The infections are commonly polymicrobial, and develop as a result of oral cavity infections, tonsilitis, laryngitis, trauma, or malignancy. Timely diagnostics and management are essential to prevent severe complications such as airway obstruction, sepsis or mediastinitis.
View Article and Find Full Text PDFClinical impacts of utilizing ceftriaxone and metronidazole versus piperacillin/tazobactam in patients diagnosed with complicated diverticulitis.
Am J Surg
January 2025
Department of Pharmacy, Mayo Clinic Health System, Eau Claire, WI, USA.
Background: The optimal antibiotic regimen to empirically treat complicated diverticulitis has not been well established in guidelines.
Methods: A 5-year retrospective cohort study was conducted with 322 patients admitted to Mayo Clinic hospitals for complicated diverticulitis. Outcomes for 89 patients treated with ceftriaxone and metronidazole were compared to 233 patients treated with piperacillin/tazobactam.
Low-level primary clarithromycin resistance of Helicobacter pylori in Reunion Island.
Infect Dis Now
January 2025
CHU Poitiers, Department of Infectious Agents, Bacteriology Department, Poitiers, France; University of Poitiers, U1070 INSERM Pharmacology of Antimicrobial Agents and Antibiotic Resistance, Poitiers, France.
Introduction: The increasing resistance of Helicobacter pylori to clarithromycin leads to an ongoing adaptation of empirical first-line treatment for H. pylori infections.
Patients And Methods: Prospective study (2022-2023) of 364 patients with no previous treatment for H.
Impact of parent-reported antibiotic allergies on paediatric Antimicrobial Stewardship Programs.
J Allergy Clin Immunol Pract
January 2025
Immunology Department, Perth Children's Hospital, Perth, Western Australia; Medical School, University of Western Australia, Australia; Immunology Department, PathWest Laboratory Medicine WA, Perth, Australia; Immunology Department, Sir Charles Gairdner Hospital, Perth, Australia. Electronic address:
Background: Antimicrobial stewardship (AMS) is crucial for optimising antimicrobial use and restraining emergence of antimicrobial resistance. The overall increase in reported antibiotic allergies in children can pose a significant barrier to AMS, but its impact on clinical AMS care in children has not been addressed.
Objective: Compare the clinical outcomes for children with a reported antibiotic allergy label (AAL) with those with no AAL reviewed by AMS.
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