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http://dx.doi.org/10.14745/ccdr.v47i09a01 | DOI Listing |
Nat Commun
January 2025
Princess Margaret Cancer Centre, 101 College Street, Toronto, ON, Canada.
Deep learning has proven capable of automating key aspects of histopathologic analysis. However, its context-specific nature and continued reliance on large expert-annotated training datasets hinders the development of a critical mass of applications to garner widespread adoption in clinical/research workflows. Here, we present an online collaborative platform that streamlines tissue image annotation to promote the development and sharing of custom computer vision models for PHenotyping And Regional Analysis Of Histology (PHARAOH; https://www.
View Article and Find Full Text PDFUrol Oncol
December 2024
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA; Cedars-Sinai Center for Outcomes Research and Education, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA. Electronic address:
Background: Guidelines for prostate cancer treatment in men with limited life expectancy are based on expert opinion. Patient preferences for when to defer treatment based on longevity are unknown. We sought to define life expectancy thresholds at which men are more likely to choose conservative management in the context of varying risks of cancer death and treatment-related side effects.
View Article and Find Full Text PDFInflamm Bowel Dis
November 2024
RMEI, Medical Education, Voorhees, NJ, USA.
Background: Despite the growing availability of advanced medical therapies for inflammatory bowel disease (IBD), significant gaps remain in treatment initiation. Targeted education and point-of-care clinical decision support may address this gap and lead to improved patient outcomes.
Methods: A multiphase IBD-focused provider education and decision support program spanning 10 years was developed consisting of (1) symposia-based education (n = 1101 learners; 2014 to 2019), (2) point-of-care education (n = 8547 learners) with clinical decision support tool (CDST) deployment (n = 11 940 users, n = 954 learners; 2019 to 2023), and (3) data-driven platform optimization (2024).
Background: Use of online crowdfunding to mitigate health-related cost burden is common in the US, but its usage among candidates for metabolic and bariatric surgery (MBS) is unknown. We aimed to identify GoFundMe campaigns fundraising for MBS and characterize sources of financial strain. We also aimed to determine factors associated with successful crowdfunding.
View Article and Find Full Text PDFPract Radiat Oncol
November 2024
Department of Radiation Oncology, University of California San Francisco, San Francisco, California. Electronic address:
Purpose: We sent surveys to a large number of radiation oncologists with active thoracic cancer practices and applied the Delphi method over 3 rounds to generate consensus dose-volume histogram metrics. We used these results to create consensus-based organs-at-risk dose constraints and target goal templates for practical implementation.
Methods And Materials: In this institutional review board-approved study, data were collected using REDCap electronic data capture on a secure server.
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