Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502893 | PMC |
| http://dx.doi.org/10.3389/fneur.2021.752463 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A methodological scoping review on EMG processing and synergy-based results in muscle synergy studies in Parkinson's disease.
Front Bioeng Biotechnol
January 2025
Institute of Intelligent Industrial Systems and Technologies for Advanced Manufacturing (STIIMA), Italian Council of National Research (CNR), Milan, Italy.
Introduction: Parkinson's Disease is the second most common neurodegenerative disease in the world. It affects mainly people over 65 and the incidence increases with age. It is characterized by motor and non-motor symptoms and several clinical manifestations.
View Article and Find Full Text PDFBehavioral analysis of motor and non-motor impairment in rodent models of Parkinson's disease.
Front Aging Neurosci
December 2024
CHU de Québec-Université Laval Research Center, Neuroscience Axis, Québec City, QC, Canada.
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by the degeneration of dopamine neurons in the substantia nigra pars compacta, leading to motor and non-motor symptoms. While motor symptoms such as rigidity, tremor, bradykinesia/akinesia, and postural instability are well-recognized, non-motor symptoms including cognitive decline, depression, and anxiety also significantly impact patients' quality of life. Preclinical research utilizing animal models has been instrumental in understanding PD pathophysiology and exploring therapeutic interventions.
View Article and Find Full Text PDFUltrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors.
Ann Rehabil Med
December 2024
Department of Rehabilitation Medicine, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea.
Objective: Tremors are caused by contractions of reciprocally innervated muscles. The role of ultrasound in diagnosing tremors has not yet been investigated, although it appears to be promising because it can visualize muscle movements. In the present study, we report four cases of tremor (Holmes' tremor, extremity tremor associated with palatal myoclonus, dystonic tremor, and tremor associated with dystonia), which were evaluated using ultrasound and treated with botulinum toxin injections.
View Article and Find Full Text PDFBiomarker Assessment in Parkinson's Disease Dementia and Dementia with Lewy Bodies by the Immunomagnetic Reduction Assay and Clinical Measures.
J Alzheimers Dis Rep
October 2024
Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Background: Plasma biomarker assays provide an opportunity to reassess whether Alzheimer's disease, Parkinson's disease dementia (PDD), and dementia with Lewy bodies (DLB) plasma biomarkers are diagnostically useful.
Objective: We hypothesized that immunomagnetic reduction (IMR) of plasma biomarkers could differentiate between patients with PDD and DLB and healthy patients when combined with established clinical testing measures.
Methods: Plasma samples from 61 participants (12 PDD, 12 DLB, 37 controls) were analyzed using IMR to quantify amyloid-β 42 (Aβ), total tau (t-tau), phosphorylated tau at threonine 181 (p-tau181), and α-synuclein (α-syn).
Non-motor symptoms in patients with Spinocerebellar ataxia type 12.
Front Neurol
October 2024
Department of Neurology, Institute of Neurosciences Kolkata, Kolkata, India.
Introduction: Spinocerebellar ataxia type 12 (SCA12) is a rare autosomal dominant neurodegenerative disorder caused by abnormal CAG repeat expansion in the gene. This disease is classically characterized by action tremor, dysarthria, ataxia, and hyperreflexia. There are limited reports regarding the non-motor symptoms in patients with SCA 12.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!