AI Article Synopsis

  • The synthesis of finely sized gold nanoparticles (Au NPs) on silica templates is essential for enhancing their effectiveness in various applications.
  • A new technique employing seed-mediated growth and interval dropping methods was developed, resulting in Au NPs with notable peroxidase-like activity, making them advantageous over other nanozymes.
  • The study demonstrated that these SiO@Au NPs are stable during long-term storage and can be reused for up to five cycles while investigating various factors that affect their activity.

Article Abstract

The precise synthesis of fine-sized nanoparticles is critical for realizing the advantages of nanoparticles for various applications. We developed a technique for preparing finely controllable sizes of gold nanoparticles (Au NPs) on a silica template, using the seed-mediated growth and interval dropping methods. These Au NPs, embedded on silica nanospheres (SiO@Au NPs), possess peroxidase-like activity as nanozymes and have several advantages over other nanoparticle-based nanozymes. We confirmed their peroxidase activity; in addition, factors affecting the activity were investigated by varying the reaction conditions, such as concentrations of tetramethyl benzidine and HO, pH, particle amount, reaction time, and termination time. We found that SiO@Au NPs are highly stable under long-term storage and reusable for five cycles. Our study, therefore, provides a novel method for controlling the properties of nanoparticles and for developing nanoparticle-based nanozymes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508978PMC
http://dx.doi.org/10.3390/ijms221910382DOI Listing

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