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Article Abstract
Herein we report a mild, general protocol for visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones. The protocol permits efficient functionalization of sulfones with a broad range of cyclic and acyclic secondary and tertiary alkyl groups and is scalable to the gram level. Its excellent functional group tolerance and mildness make it suitable for late-stage functionalization of natural products and drug molecules.
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| http://dx.doi.org/10.1039/d1ob01806j | DOI Listing |
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