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Functional hydrogel empowering 3D printing titanium alloys.
Mater Today Bio
February 2025
Department of Orthopedics, The Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Titanium alloys are widely used in the manufacture of orthopedic prosthesis given their excellent mechanical properties and biocompatibility. However, the primary drawbacks of traditional titanium alloy prosthesis are their much higher elastic modulus than cancellous bone and poor interfacial adhesion, which lead to poor osseointegration. 3D-printed porous titanium alloys can partly address these issues, but their bio-inertness still requires modifications to adapt to different physiological and pathological microenvironments.
View Article and Find Full Text PDF[Empowering patients through app-based cochlear implant self-adjustment].
HNO
January 2025
Deutsches Hörzentrum der Medizinischen Hochschule Hannover, Karl-Wiechert-Allee 3, 30625, Hannover, Deutschland.
Treatment of patients with severe hearing loss or deafness using cochlear implants (CI) is nowadays clinical routine. In the Hannover Medical School alone, more than 500 patients are treated with CI annually, meaning that the pool of patients with CI increases significantly each year. Worldwide, there are over 1 million patients with a CI system; in Germany the figure is estimated at over 60,000.
View Article and Find Full Text PDFAdvancements and Challenges in the Management of Prosthetic Valve Endocarditis: A Review.
Pathogens
November 2024
Department of Cardiac Surgery, Centre Cardiologique du Nord, 93200 Saint-Denis, France.
Prosthetic valve endocarditis (PVE) is the medical term used to describe a focus of infection involving a valvular substitute within the heart. It is a significant concern in the field of cardiology, and the epidemiology of PVE has seen notable developments over the last five decades. The disease currently affects an older demographic and is becoming increasingly prevalent in patients with transcatheter-implanted valves.
View Article and Find Full Text PDFDefining the ideal trajectory into the inner ear in image-guided cochlear implant surgery.
Sci Rep
November 2024
Vrije Universiteit Brussel, Brussels Health Campus, Brussels, Belgium.
The aim of robot-assisted cochlear implant surgery (RACIS) is to access the inner ear with minimal trauma. High-resolution imaging, empowered with a highly accurate navigation system can enable the planning of a direct keyhole drilling trajectory toward the inner ear. The time has come to (re)define the ideal trajectory into the inner ear with robot-assisted tools that can drill with the highest accuracy.
View Article and Find Full Text PDFA LDH-Derived Metal Sulfide Nanosheet-Functionalized Bioactive Glass Scaffold for Vascularized Osteogenesis and Periprosthetic Infection Prevention/Treatment.
Adv Sci (Weinh)
October 2024
Department of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, P. R. China.
Periprosthetic infection and prosthetic loosing stand out as prevalent yet formidable complications following orthopedic implant surgeries. Synchronously addressing the two complications is long-time challenging. Herein, a bioactive glass scaffold (BGS) functionalized with MgCuFe-layered double hydroxide (LDH)-derived sulfide nanosheets (BGS/MCFS) is developed for vascularized osteogenesis and periprosthetic infection prevention/treatment.
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