AI Article Synopsis
- The study aimed to explore the occurrence of absent Bell's phenomenon (BP) in patients with thyroid eye disease (TED) and its connection to inferior rectus muscle hypertrophy and clinical features.
- Out of 104 TED patients assessed, 14 were found to have absent BP, but there were no significant differences in thyroid function tests or muscle volume compared to patients with BP.
- The presence of symptoms like diplopia, elevation limitation, and upper eyelid retraction were identified as risk factors for absent BP, indicating that factors like fibrosis rather than muscle size might be involved.
Article Abstract
Background: To investigate the incidence of absent Bell's phenomenon (BP) and the relationship between absent BP and inferior rectus muscle hypertrophy and other clinical features in patients with thyroid eye disease (TED).
Methods: A total of 104 patients who were first diagnosed with TED between January and December 2014 were included. Inferior rectus muscle area and associations with clinical features of TED and thyroid function test including thyroid specific antibodies were compared between patients with TED with and without BP. The volume of the inferior rectus muscle was calculated by adding up all the cross-sectional areas measured on sagittal CT images.
Results: Among the 104 patients, 14 had absent BP (13.5%), 12 with bilateral and two with unilateral. There was no significant difference in thyroid function test, presence of TSIs, exophthalmos, or volume of inferior rectus muscle measured in CT scans (P > 0.05). Incidence of diplopia, elevation limitation, and upper eyelid retraction were risk factors of absent BP in TED patients (by logistic regression analysis, P < 0.05).
Conclusions: Inferior rectus muscle hypertrophy was not the cause of absent BP in TED patients. Fibrosis and tightening of the inferior rectus muscle, lower eyelid, and surrounding orbital tissues, rather than inferior rectus muscle hypertrophy, might be related to absent BP in TED patients.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507383 | PMC |
| http://dx.doi.org/10.1186/s12886-021-02107-x | DOI Listing |
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