The normalized limit of detection in NMR spectroscopy.

We derive the normalized limit of detection for frequency space (nLOD) as a parameter to measure the sensitivity of an NMR spectroscopy setup. nLOD is independent of measurement settings such as bandwidth or number of measurement points, and allows to compare performances of different setups. We demonstrate the usefulness of the new nLOD by comparing the sensitivity of NMR setups from various publications, which all use microcoils. Finally, we want to propose a standard measurement and report format for the sensitivity of new NMR setups.