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The Role of Bitter-Tasting Substances in Salivation and Swallowing: Results of the Pilot Study.
Foods
January 2025
Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow 109240, Russia.
The aim of this study was to investigate the effects of caffeine, vanillin, and epigallocatechin gallate on salivation and swallowing and to find ways to correct their negative effects. Solutions of these substances with an equivalent intensity of bitter taste were compared for this purpose. To compensate for their effect, solutions of adenosine monophosphate, saliva substitute, and their combination were used.
View Article and Find Full Text PDFSocial jetlag decreases across the lifespan: A prospective big data analysis of objective sleep metrics.
J Sleep Res
January 2025
Department of Neurology, University of Washington School of Medicine, Seattle, Washington, USA.
Changes in social zeitgebers across the lifespan affect the interaction between biological and social clocks, potentially contributing to social jetlag. Extant literature suggests a reduction in social jetlag given declining social obligations occurring after retirement, but is limited to self-reported methods and cross-sectional designs. Leveraging longitudinal and ecologically valid data from consumer sleep technology, we analysed objective sleep data from 2439 users of the polysomnography-validated SleepScore mobile application, encompassing 500,415 total nights recorded.
View Article and Find Full Text PDFAssociation of caffeine intake and sleep duration with bone mineral density: a cross-sectional study from National Health and Nutrition Examination Survey between 2011 and 2018.
BMC Musculoskelet Disord
January 2025
Department of Orthopedics, Wuhan Fourth Hospital, Wuhan fourth hospital, No. 473, Hanzheng Street, Qiaokou District, Wuhan, China.
Objective: The association between sleep duration, caffeine intake, and bone mineral density (BMD) is not well understood, with previous studies providing controversial results. This study explores the associations among caffeine intake, sleep duration, and BMD.
Methods: Data were sourced from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018, including 13,457 participants who self-reported sleep duration and caffeine intake, with BMD measured via dual X-ray absorptiometry.
The effect of an additional pre-extubational loading dose of caffeine citrate on mechanically ventilated preterm infants (NEOKOFF trial): Study protocol for a multicenter randomized clinical trial.
PLoS One
January 2025
Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Background: Minimizing the duration of mechanical ventilation is one of the most important therapeutic goals during the care of preterm infants at neonatal intensive care units (NICUs). The rate of extubation failure among preterm infants is between 16% and 40% worldwide. Numerous studies have been conducted on the assessment of extubation suitability, the optimal choice of respiratory support around extubation, and the effectiveness of medical interventions.
View Article and Find Full Text PDFBetter sleep hygiene is associated with better sleep health in mining shift workers in Australia.
J Sleep Res
January 2025
School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Australia's mine sites are largely situated in remote locations and operate around the clock. Many shift workers fly to site, where they work 12-hr shifts and sleep in camp accommodation before they return home for the period rostered off work. Mining shift workers experience poor sleep, yet limited research is available on contributing factors.
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