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ANCA Negative Vasculitis Manifesting as Pulmonary-Renal Syndrome in a Patient with Chronic Osteomyelitis.
J Assoc Physicians India
March 2025
Senior Consultant, Department of Medicine, Sir Ganga Ram Hospital, Delhi, India.
A man in his early 60s, with a history of obstructive airway disease and hypertension, had a fall from a height 1 year ago. He developed a fracture of the left distal tibia and fibula, for which open reduction and internal fixation (ORIF) was done. Since then, he has had persistent pain and discharge from the implant site, for which multiple antibiotics were given and debridement was done numerous times.
View Article and Find Full Text PDFGiant retroperitoneal liposarcoma with colonic infiltration as a cause of gastrointestinal bleeding: Case report and literature review.
Int J Surg Case Rep
March 2025
Faculty of Medicine, Pontifical Xavierian University, Bogotá, Colombia.
Introduction: Retroperitoneal liposarcomas are rare malignant tumors that often present asymptomatically until advanced stages. Giant liposarcomas exceeding 30 cm are particularly uncommon, and colonic infiltration causing gastrointestinal bleeding is extremely rare, with only a few cases documented in the literature.
Case Presentation: A 78-year-old female presented with hematochezia, constipation, and diffuse abdominal pain.
Quantifying multi-institutional ADC measurement variability of 1.5 T MR-Linacs: A phantom and in vivo study.
Med Phys
March 2025
GenesisCare, Sydney, New South Wales, Australia.
Background: Diffusion-weighted imaging (DWI), a quantitative magnetic resonance imaging (qMRI) technique, has the potential to aid in disease characterization and treatment response monitoring. MR-Linacs (MRLs) enable simultaneous DWI acquisitions during radiotherapy, uniquely aiding in the collection of large-scale datasets for imaging biomarkers, such as the DWI-derived apparent diffusion coefficient (ADC), without additional patient burden. However, the limited data reporting on variability in MRL scanner performance characteristics, and a lack of established clinical trial quality assurance (QA) procedures, are barriers to this route for biomarker validation.
View Article and Find Full Text PDFReview of the Imaging Modalities in the Gynecological Neoplasms During Pregnancy.
Cancers (Basel)
February 2025
School of Medicine, National and Kapodistrian University of Athens, Aretaieon Hospital, 11527 Athens, Greece.
The aim of this review is to provide an update on the imaging triage, safety considerations, and cancer-imaging features of common and uncommon gynecological tumors during pregnancy. Clinical examination can be inconclusive, especially for the evaluation of intra-abdominal diseases since symptoms related to cancer such as fatigue, vomiting, or nausea overlap with common pregnancy-associated symptoms. Delayed pregnancy, advanced maternal age, and improvements in diagnostic imaging in developed countries have increased the incidence of cancer diagnosis in gravid populations.
View Article and Find Full Text PDFAbdominal aortic aneurysm is a systemic and generalized arteriomegaly in mice and humans.
Sci Rep
March 2025
Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains largely unclear, evidence is accumulating to suggest the systemic nature of this disease. Here, we comprehensively assessed the whole aortic tree with its major branches based on computed tomography angiography (CTA) in AAA patients compared to ascending thoracic aortic aneurysm (ATAA) patients and nonaneurysmal controls, as well as in an original mouse model of AAA in Lkb1;Myh11-Cre/ERT2 mice. The morphology and dimensions of the whole aorta (at different levels) and its major branches were compared among 47 AAA patients, 47 ATAA patients, and 46 nonaneurysmal controls based on CTA images.
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