Food Chem
Institute of Agrochemistry and Food Technology (IATA-CSIC), C/Agustin Escardino, 7, 46980 Paterna, Spain. Electronic address:
Published: March 2022
Phenolic acids are involved in modulating the activity of starch digestive enzymes but remains unclear if their interaction with enzymes or starch is governing the inhibition. The potential inhibition of nine phenolic acids against α-amylase and α-glucosidase was studied applying different methodologies to understand interactions between phenolic acids and either enzymes or substrates. Vanillic and syringic acids were prone to interact with α-amylase requiring low half-maximum inhibitory concentration (IC) to inhibit starch hydrolysis. Nevertheless, the initial interaction of phenolic acids with starch somewhat obstructed their interaction with starch, requiring 10 times higher IC, with the exception of chlorogenic and gallic acid. The study demonstrates that 10% of the phenolic acids were retained during starch gelatinization. Those effects were not really evident with α-glucosidase, likely due to the small molecular size of maltose substrate. Phenolic acids with > 1 hydroxyl group like caffeic and protocatechuic acids showed the lowest IC against α-glucosidase.
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http://dx.doi.org/10.1016/j.foodchem.2021.131231 | DOI Listing |
Funct Integr Genomics
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Department of Zoology, University of Gour Banga, Malda, 732103, India.
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Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
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College of Horticulture, Hebei Agricultural University, Baoding, China.
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Laboratory of Plant Anatomy and Morphology, Komarov Botanical Institute of the Russian Academy of Sciences, Professor Popov Street, 2, 197376, St. Petersburg, Russia.
Previously, it was found that four types of glandular trichomes (GTs) are developed on the surface of all aerial organs in Doronicum species. A detailed study of leaves had shown that only two types of GTs form in them. Nothing was known about any differences of GTs on vegetative and reproductive organs.
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January 2025
Department of Chemistry, Nanchang University, 999 Xuefu Avenue, Nanchang 330031, China. Electronic address:
Zein and its complexes have been considered as promising carriers for encapsulating and delivering various biological active ingredients, however, there still have some issues about Zein-based drug delivery systems should be considered, including poor colloidal stability, low drug encapsulation efficiency as well as rapid initial drug release, and uncontrollable release. In this work, we reported for the first time that hyperbranched polymers (HPG) functionalized Zein with terminal alkyne (Zein-HPG-PA) can be used for loading anticancer agent curcumin (CUR) via a facile phenol-yne click reaction. The resultant product (Zein-HPG-PA@CUR) displays high drug loading capacity, small particle size and excellent water dispersibility.
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