The photophysical and photochemical properties of two Pt(IV)Re(I) conjugates were studied both experimental and computational methods. Both conjugates exhibit modest photocytotoxicity against ovarian cancer cells. X-ray fluorescence microscopy showed that Pt and Re colocalize in cells whether they had been irradiated or not. This work demonstrates the potential of photoactivated multilimetallic agents for combating cancer.
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http://dx.doi.org/10.1039/d1cc04669a | DOI Listing |
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