Photochemistry and anticancer activity of Pt(IV)Re(I) conjugates.

Chem Commun (Camb)

Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

Published: October 2021

The photophysical and photochemical properties of two Pt(IV)Re(I) conjugates were studied both experimental and computational methods. Both conjugates exhibit modest photocytotoxicity against ovarian cancer cells. X-ray fluorescence microscopy showed that Pt and Re colocalize in cells whether they had been irradiated or not. This work demonstrates the potential of photoactivated multilimetallic agents for combating cancer.

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Source
http://dx.doi.org/10.1039/d1cc04669aDOI Listing

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