: Ectopic breast fibroadenoma is a rare benign neoplasm that may mimic pathological lymph node clinically and on imaging.
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http://dx.doi.org/10.5334/jbsr.2546 | DOI Listing |
Front Oncol
December 2024
Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, China.
Male breast cancer represents only 1% of all breast malignancies, with ectopic breast cancer in men being even rarer and highly prone to diagnostic challenges. Extramammary Paget's disease (EMPD), a rare cutaneous tumor with non-specific clinical symptoms, is susceptible to misdiagnosis. This report discusses the case of an older male patient who presented with a scrotal mass, later identified as ectopic breast invasive adenocarcinoma upon pathological examination post-lesion excision.
View Article and Find Full Text PDFCureus
November 2024
Department of Pathology, Father Muller Medical College, Mangalore, IND.
Axillary swellings, particularly in women, often raise suspicion due to the high association of such swellings with breast carcinoma manifesting as metastatic lymph node involvement. Tuberculous lymphadenopathy is one of the primary diagnoses in India. Fibroadenomas are common benign breast tumors, but their occurrence in the axilla, arising from ectopic breast tissue (EBT), is rare and may present a diagnostic challenge.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Center of Marine Sciences (CCMAR), University of Algarve, 8005-139 Faro, Portugal.
Matrix Gla protein (MGP) is a vitamin K-dependent γ-carboxylated protein that was initially identified as a physiological inhibitor of ectopic calcification, primarily affecting cartilage and the vascular system. Mutations in the gene were found to be responsible for the Keutel syndrome, a condition characterized by abnormal calcifications in the cartilage, lungs, brain, and vascular system. has been shown to be dysregulated in several tumors, including cervical, ovarian, urogenital, and breast cancers.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Clinic of Surgical Semiotics and Thoracic Surgery-1, Department IX-Surgery-1, "Victor Babes" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Accessory breast cancer cases are rarely reported in the literature. Of the reported cases, the predominantly available ones are those localized in the axillary region. We present here a very rare case of metastatic accessory breast cancer.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Hypercalcemia is a common metabolic complication associated with malignancies, particularly in solid tumors, such as lung and breast cancers. However, its occurrence in hematologic malignancies, including diffuse large B-cell lymphoma (DLBCL), is rare. The pathophysiology of hypercalcemia in lymphomas is often related to the secretion of parathyroid hormone (PTH)-related peptide (PTHrP).
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