Diabetic foot is a serious infection of the lower limbs. It is caused by diabetic neuropathy and vascular disease. It is also the primary cause of disability and death in patients with severe diabetes, so prompt treatment is essential for positive outcomes. The clinical use of nano-silver dressings can be considered to further optimize the treatment process and improve the treatment efficacy in diabetic foot patients. Nano-silver dressings have a larger contact surface and a stronger bactericidal effect when compared to ordinary silver dressings. Besides, it can be disinfected repeatedly to better wound infection control and promote wound healing. The current article discusses the pathogenesis of diabetic foot, diabetic foot dressing treatment, the application of nanotechnology in diabetic foot treatment, the efficacy evaluation of different dressings, and the practical prospects of adopting nanotechnology in the treatment of diabetic foot.
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http://dx.doi.org/10.2147/DMSO.S330322 | DOI Listing |
BMC Endocr Disord
January 2025
Burn and Wound Repair Department, Fujian Medical University Union Hospital, Fuzhou, China.
Background: Diabetic foot ulcers (DFUs) are characterized by dynamic wound microbiome, the timely and accurate identification of pathogens in the clinic is required to initiate precise and individualized treatment. Metagenomic next-generation sequencing (mNGS) has been a useful supplement to routine culture method for the etiological diagnosis of DFUs. In this study, we utilized a routine culture method and mNGS to analyze the same DFU wound samples and the results were compared.
View Article and Find Full Text PDFJ Imaging Inform Med
January 2025
Computer Science Department, University of Geneva, Geneva, Switzerland.
Accurate wound segmentation is crucial for the precise diagnosis and treatment of various skin conditions through image analysis. In this paper, we introduce a novel dual attention U-Net model designed for precise wound segmentation. Our proposed architecture integrates two widely used deep learning models, VGG16 and U-Net, incorporating dual attention mechanisms to focus on relevant regions within the wound area.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard (Deemed University), M. B. Road, New Delhi 110062, India. Electronic address:
Infect Dis Rep
January 2025
Diabetic Foot Unit, Clínica Universitaria de Podología, Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
This systematic review reports on treatments for onychomycosis in patients with diabetes and the drug interactions with other drugs in regard to the complicated diabetic patient profile. The recommendations in the preferred reporting items for systematic reviews and meta-analysis (PRISMA) checklist were applied and the included studies were evaluated using the Consolidated Standards of Reporting Trials (CONSORT) statement and the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Searches were conducted in November 2023, using the PubMed (Medline), Scopus, Cochrane Library, and Web of Science databases; studies on antifungal treatments for onychomycosis in patients with diabetes were included.
View Article and Find Full Text PDFJ Pain Res
January 2025
Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Province, 530021, People's Republic of China.
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