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| http://dx.doi.org/10.1093/plphys/kiab257 | DOI Listing |
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Alzheimers Dement
December 2024
Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Understanding the dynamics of markers throughout Alzheimer's disease (AD) progression in a representative population is critical for early detection of AD. Most existing studies used a single cohort to model the dynamics of AD-related markers, which may lead to biased and unreproducible results. The Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium (ADSP-PHC) harmonized rich endophenotype data across multiple cohort studies, providing valuable resources for ADRD research.
View Article and Find Full Text PDFBackground: Optimizing outcomes of hospitalized patients anchors on standardizing processes in medical management, interventions to reduce the risk of decompensation, and prompt intervention when a patient decompensates.
Methods: A quality improvement initiative (optimized sepsis and respiratory compromise management, reducing health care-associated infection and medication risk, swift management of the deteriorating patient, feedback on performance, and accountability) was implemented in a multistate health system. The primary outcome was risk-adjusted in-hospital mortality.
Prognosis and diagnosis prediction of lung adenocarcinoma outcome based on a novel model anchored in circadian clock-related genes.
J Cell Commun Signal
December 2024
International CCN Society Nice France.
The transition of JCCS from Springer to Wiley was rich in future prospects and was confirmed by the Journal reorganization launched in 2019. However, in spite of my recently renewed demand, the "B&B" section of the Journal (Bits and Bytes not be confused with Bed and Breakfast, albeit…) did not fit into the Wiley Publishing categories and had to be dropped, to the great disappointment of many authors and our readership. This Editorial will fill the gap by discussing new published aspects on the topic of the connections existing between circadian cellular signaling and cancer prognosis, with the identification of eight genetically significant clock-related genes in lung cancer.
View Article and Find Full Text PDFEnhancing Efficiency in Meniscal Repair: A Novel In-House Vacuum Suction Technique for Suture Loading in Long Hollow Needles and Devices.
Cureus
October 2024
CASCO Department, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Galeazzi, Milan, ITA.
Background: Suture-loaded long hollow needles are used in arthroscopic surgery to pass or retrieve sutures and in meniscal repair surgeries. However, manual suture loading can be time-consuming and challenging, especially with finer sutures. We present a novel technique using vacuum suction to simplify and expedite suture loading in hollow needles and similar devices.
View Article and Find Full Text PDFComparative Study of Arctic Front Advance Pro and POLARx Cryoballoons for Linear Ablation of the Left Atrial Roof.
Pacing Clin Electrophysiol
January 2025
Heart Center, Japan Red Cross Yokohama City Bay Hospital, Yokohama, Japan.
Article Synopsis
- This study investigates the effectiveness of cryoballoon ablation (CBA) of the left atrial roof using the POLARx catheter compared to the AFA-Pro in patients with persistent atrial fibrillation.
- The results show that POLARx achieved a complete conduction block more effectively and maintained a significantly lower cryoballoon temperature during the procedure compared to AFA-Pro.
- As a result, POLARx eliminates the need for rapid right ventricular pacing, making the procedure simpler and more efficient for achieving the desired outcomes.
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