Critical power (CP) delineates the heavy and severe exercise intensity domains, and sustained work rates above CP result in an inexorable progression of oxygen uptake to a maximal value and, subsequently, the limit of exercise tolerance. The finite work capacity above CP, W', is defined by the curvature constant of the power-duration relationship. Heavy or severe exercise in a hot environment generates additional challenges related to the rise in body core temperature (T) that may impact CP and W'. The purpose of this study was to determine the effect of elevated T on CP and W'. CP and W' were estimated by end-test power (EP; mean of final 30 s) and work above end-test power (WEP), respectively, from 3-min "all-out" tests performed on a cycle ergometer. Volunteers ( = 8, 4 female) performed the 3-min tests during a familiarization visit and two experimental visits (thermoneutral vs. hot, randomized crossover design). Before experimental 3-min tests, the subjects were immersed in water (thermoneutral: 36°C for 30 min; hot: 40.5°C until T was ≥38.5°C). Mean T was significantly greater in the hot condition than in the thermoneutral condition (38.5 ± 0.0°C vs. 37.4 ± 0.2°C; means ± SD, < 0.01). All 3-min tests were performed in an environmental chamber [thermoneutral: 18°C, 45% relative humidity (RH); hot: 38 °C, 40% RH]. EP was similar between thermoneutral (239 ± 57 W) and hot (234 ± 66 W; = 0.55) conditions. WEP was similar between thermoneutral (10.9 ± 3.0 kJ) and hot conditions (9.3 ± 3.6; = 0.19). These results suggest that elevated T has no significant impact on EP or WEP. The parameters of the power-duration relationship (critical power and W') estimated by a 3-min all-out test were not altered by elevated body core temperature as compared with a thermoneutral condition.
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http://dx.doi.org/10.1152/japplphysiol.00253.2021 | DOI Listing |
Sci Rep
December 2024
Centre for Ore Deposit and Earth Sciences, School of Natural Sciences, University of Tasmania, Hobart, Australia.
Volcanic stratigraphy reconstruction is traditionally based on qualitative facies analysis complemented by geochemical analyses. Here we present a novel technique based on machine learning identification of crystal size distribution to quantitatively fingerprint lavas, shallow intrusions and coarse lava breccias. This technique, based on a simple photograph of a rock (or core) sample, is complementary to existing methods and allows another strategy to identify and compare volcanic rocks for stratigraphic correlation.
View Article and Find Full Text PDFSci Rep
December 2024
College of Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Virtual Reality (VR) technology enables users to immerse themselves in computer-generated environments, providing experiences that are otherwise difficult to attain in real life. VR has expanded from gaming into diverse fields, even the medical sector. In medical education, VR is mainly employed for anatomy and surgical practice, enhancing the learning experience by offering three-dimensional visualization and interaction with human structures.
View Article and Find Full Text PDFBMC Surg
December 2024
Department of Nursing, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Lanzhou, China.
Perioperative hypothermia is a frequent clinical complication resulting from the cold environment of the operating room and prolonged skin exposure, leading to adverse outcomes and increased healthcare burdens. To address this issue, this narrative review discusses in detail the currently common warming strategies for perioperative hypothermia .Forced air warming (FAW) systems are widely recognized as the most effective intervention for maintaining core body temperature.
View Article and Find Full Text PDFJ Mol Diagn
December 2024
The AMP Clinical Genomics Bioinformatician Body of Knowledge (BoK) Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, MD, USA; University of North Carolina School of Medicine, Lineberger Comprehensive Cancer Center.
The use of next-generation sequencing (NGS) and other high-throughput technologies in the clinical molecular diagnostics laboratory requires the application of bioinformatics pipelines and other computational tools to analyze, visualize, and store these clinical data. Clinical Bioinformaticians, individuals with the skills to develop, validate, and deploy these tools in a clinical setting, are needed to ensure that these molecular diagnostic technologies can be appropriately used for clinical care. Building on existing expertise in informatics, NGS, and clinical molecular diagnostics, the Association for Molecular Pathology (AMP) has generated a series to establish an initial Clinical Bioinformatician Body of Knowledge.
View Article and Find Full Text PDFNeurochem Int
December 2024
Department of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. Electronic address:
In glioblastoma, glioma-associated microglia/macrophages (GAMs) represent the major population of tumor infiltrating cells, with up to one half of the cells of the tumor mass. Recent studies have shown that microglia are involved in the maintenance of immunological homeostasis and protection against autoimmunity. However, despite the growing body of evidence on the topic, many aspects are yet to be clarified.
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