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http://dx.doi.org/10.1007/s12035-021-02577-6 | DOI Listing |
Heliyon
December 2024
Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, 116029, China.
[This corrects the article DOI: 10.1016/j.heliyon.
View Article and Find Full Text PDFRedox Biol
February 2025
Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea; School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address:
The dynamic equilibrium between acetylation and deacetylation is vital for cellular homeostasis. Parkinson's disease (PD), a neurodegenerative disorder marked by α-synuclein (α-syn) accumulation and dopaminergic neuron loss in the substantia nigra, is associated with a disruption of this balance. Therefore, correcting this imbalance with histone deacetylase (HDAC) inhibitors represents a promising treatment strategy for PD.
View Article and Find Full Text PDFFront Psychiatry
November 2024
College of Physical Education, Yangzhou University, Yangzhou, China.
Drug addiction often correlates with criminal behavior. When investigating criminal behavior among individuals grappling with drug addiction, it becomes crucial to scrutinize the influence of dopamine. Substances such as heroin, morphine, methamphetamine and other drugs can cause abnormal dopamine secretion when people are addicted to them, which promotes changes in the brain's reward circuit and emotional balance, thereby increasing susceptibility to criminal behavior.
View Article and Find Full Text PDFPsychol Med
November 2024
Orygen, Parkville, Melbourne, VIC 3052, Australia.
Background And Hypothesis: Transition to psychosis rates within ultra-high risk (UHR) services have been declining. It may be possible to 'enrich' UHR cohorts based on the environmental characteristics seen more commonly in first-episode psychosis cohorts. This study aimed to determine whether transition rates varied according to the accumulated exposure to environmental risk factors at the individual (migrant status, asylum seeker/refugee status, indigenous population, cannabis/methamphetamine use), family (family history or parental separation), and neighborhood (population density, social deprivation, and fragmentation) level.
View Article and Find Full Text PDFJ Forensic Sci
January 2025
School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Surface-enhanced Raman spectroscopy (SERS) was utilized to measure low-level fentanyl concentrations mixed in common cutting agents, cocaine, 3,4-methylenedioxymethamphetamine (MDMA), methamphetamine, and caffeine. Mixtures were prepared with a fentanyl concentration range of 0-339 μM. Data was initially analyzed by plotting the area of a diagnostic peak (1026 cm) against concentration to generate a calibration model.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!