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Analysis of Morphological Changes in the CNS and Internal Organs of Macaca mulatta Monkeys after Intracerebral Injection of a Low-Attenuated Rubella Virus Strain. | LitMetric
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Analysis of Morphological Changes in the CNS and Internal Organs of Macaca mulatta Monkeys after Intracerebral Injection of a Low-Attenuated Rubella Virus Strain.

O A Shamsutdinova D V Bulgin D D Karal-Ogly I N Lavrent'eva

Bull Exp Biol Med

Pasteur St. Petersburg Research Institute of Epidemiology and Microbiology, St. Petersburg, Russia.

Published: September 2021

We studied the localization and severity of morphological changes in CNS and internal organs of animals intacerebrally infected with a low-attenuated rubella virus strain "Orlov-14". The data obtained can be used as morphological criteria reflecting low level of attenuation of rubella virus strains to improve the control of the safety of attenuated strains of live rubella vaccines.

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http://dx.doi.org/10.1007/s10517-021-05291-4DOI Listing

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