Wernicke's encephalopathy in a rectal cancer patient with atypical radiological features: A case report.

World J Clin Cases

Department of Neurology, The Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.

Published: September 2021

Background: Wernicke's encephalopathy is a disease caused by thiamine deficiency. The lesions usually involve the periphery of the aqueduct, midbrain, tectum, third ventricle, papillary body, and thalamus. It is very rare to affect the vermis and cerebellar hemispheres.

Case Summary: We report a 77-year-old female patient admitted to the emergency department of our hospital for 2 d of unconsciousness. Brain magnetic resonance imaging showed increased diffusion weighted imaging signals in the bilateral thalamus, periventricular regions of the third ventricle, corpora quadrigemina, vermis, and cerebellar hemispheres. Wernicke's encephalopathy was considered. She was given thiamine therapy and became conscious after the treatment.

Conclusion: Wernicke's encephalopathy may have various imaging manifestations. Clinicians should keep in mind that Wernicke's encephalopathy may occur in patients who experience prolonged periods of malnutrition.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464465PMC
http://dx.doi.org/10.12998/wjcc.v9.i25.7600DOI Listing

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