Background: This case study describes an atypical presentation of avascular necrosis (AVN) of the first metatarsal head, which is largely unfounded in the literature.
Case Summary: A healthy 24-year-old female initially presented with pain at the first metatarsophalangeal joint (MTPJ) and was diagnosed with AVN by physical examination and magnetic resonance imaging. The patient demonstrated atypically poor progress in recovery, despite being in otherwise good health and being of young age, with no history of corticosteroid or alcohol use. The patient also did not have any history or clinical features of autoimmune disease or vasculitis, such as systemic lupus erythematosus. The patient was managed with conservative treatment for 18 mo, which allowed for gradual return of full range of motion of the first MTPJ and subsiding pain, permitting the patient to return to high-intensity sports training and full weight-bearing. Throughout her recovery, many differential diagnoses were ruled out through specific investigations leading to further reinforcement of the diagnosis of AVN of the 1 metatarsal head.
Conclusion: Atypical AVN may occur with no predisposing risk factors. Treatment is mainly conservative, with unclear guidelines in literature on management.
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http://dx.doi.org/10.12998/wjcc.v9.i25.7445 | DOI Listing |
Orthop Traumatol Surg Res
January 2025
CHRU de Nancy, Department of Orthopedic, Traumatological and Arthroscopic Surgery, Hôpital Central, 29 Av. du Maréchal de Lattre de Tassigny, 54000 Nancy, France. Electronic address:
Introduction: The indications for total knee arthroplasty (TKA) are expanding to include younger and more active patients. Several recent studies have warned of a higher revision rate and lower patient satisfaction in younger patients. The aim of this study was to assess the survival of TKAs in patients under the age of 55 and to determine the risk factors for revision and complications.
View Article and Find Full Text PDFInjury
January 2025
Royal College of Surgeons in Ireland, Dublin, Ireland. Electronic address:
Background: Femoral neck fractures, particularly Pauwels type II and III, pose significant challenges due to their vertical instability and susceptibility to complications such as non-union and avascular necrosis (AVN). Medial buttress plates (MBPs) have emerged as a promising adjunct in fixation, offering biomechanical advantages by neutralizing shearing forces and enhancing stability. However, the clinical efficacy of MBPs across different fixation techniques, plate configurations, and positioning remains unclear.
View Article and Find Full Text PDFJ Bone Miner Metab
January 2025
Medical Faculty, Department of Pediatric Metabolism and Nutrition, Ege University, Izmir, 35040, Turkey.
Introduction: Gaucher disease (GD) is a lysosomal storage disorder causing systemic and skeletal complications. This study evaluates bone health in adult GD type 1 patients, focusing on skeletal complications, bone mineral density (BMD), and biochemical markers.
Material And Methods: A cohort of adult GD type 1 patients followed up at Ege University Pediatric Metabolism Department were retrospectively examined.
J Orthop Surg Res
January 2025
Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, Liaoning Province, China.
Objective: This study aimed to evaluate the clinical effectiveness of the femoral neck system (FNS) compared to four cannulated compression screws (CCSs) for managing Pauwels type III femoral neck fractures in young patients.
Methods: A retrospective analysis was conducted on young patients with Pauwels type III femoral neck fractures treated at our hospital from January 2021 to December 2022. Patients were categorized into two groups based on their respective internal fixation methods: the FNS group (32 cases) and the CCSs group (41 cases).
Genomics
January 2025
Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. Electronic address:
Osteonecrosis of the femoral head (ONFH) is a destructive bone disease, and overuse of alcohol is one of the major contributing factors. Although mesenchymal stem cells (MSCs) and their exosomes have been reported to attenuate ONFH, the potential mechanisms of alcohol-induced ONFH (AONFH) are unclear. Here, we isolated and identified human umbilical cord MSCs-derived exosomal (hucMSCs-exos) miR-25-3p.
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