Light has many non-visual effects on human physiology, including alterations in sleep, mood, and alertness. These effects are mainly mediated by photoreceptors containing the photopigment melanopsin, which has a peak sensitivity to short wavelength ('blue') light. Commercially available light sensors are commonly wrist-worn and report photopic illuminance and are calibrated to perceive visual brightness and hence cannot be used to investigate the non-visual impacts of light. In this paper, we report the development of a wearable spectrophotometer designed to be worn as a pendant or affixed to clothing to capture spectral power density data close to eye level in the visible wavelength range 380-780 nm. From this, the relative impact of a given light stimulus can be determined for each photoreceptive input in the human eye by calculating effective illuminances. This device showed high accuracy for all effective illuminances while measuring a range of commonly encountered light sources by calibrating for directional response, dark noise, sensor saturation, non-linearity, stray-light and spectral response. Features of the device include IoT-integration, onboard data storage and processing, Bluetooth Low Energy (BLE) enabled data transfer, and cloud storage in one cohesive unit.
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http://dx.doi.org/10.1364/OE.431373 | DOI Listing |
Dent Mater
January 2025
Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, room 352, BC V6T-1Z3, Canada. Electronic address:
Objectives: This study aimed to assess the potential of experimental dental resins containing ZnO nanoparticles (ZnO-NPs) for antimicrobial photodynamic therapy (aPDT) as a functional tool for the modulation of cariogenic biofilm in long-term.
Methods: Minimum inhibitory and bactericidal concentrations (MIC/MBC) of ZnO-NPs against Streptococcus mutans were initially determined under different energy densities of blue LED irradiation (0.00, 1.
Int J Biol Macromol
January 2025
School of Food and Biological Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China. Electronic address:
Flexible smart sensing materials are gaining tremendous momentum in wearable and bionic smart electronics. To satisfy the growing demand for sustainability and eco-friendliness, biomass-based hydrogel sensors for green and biologically safe wearable sensors have attracted significant attention. In this work, we have prepared MCC/PAA/AgNWs/CNTs hydrogel sensors with excellent conductive sensing properties by a simple physical blending method.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Orthopaedics Department of Traditional Chinese Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui 750004, China; Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui 750004, China. Electronic address:
Population exposure to plastics is increasing, and plasticizers are frequently detected in humans as important ingredients of plastic products. However, patterns of exposure to harmful ingredients of plastics and their effects on neurofilament light chain (NFL), a marker of active brain pathology, are currently inconclusive. Herein, we employed a range of statistical methods to thoroughly investigate the impact of 24 plastic hazardous ingredients and their varying exposure patterns on NFL concentrations in the blood of the general population in 533 participants.
View Article and Find Full Text PDFCurr Opin Cell Biol
January 2025
Departments of Physics, Cell Biology and Biochemistry, Emory University, Atlanta, GA 30322, USA. Electronic address:
Twinfilin is an evolutionarily conserved actin-binding protein initially mischaracterized as a tyrosine kinase but later recognized as a key regulator of cellular actin dynamics. As a member of the ADF-H family, twinfilin binds both actin monomers and filaments. Its role in sequestering G-actin is well-established, but its effects on actin filaments have been debated.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
College of Polymer Science & Engineering, Sichuan University, Chengdu 610065, China. Electronic address:
While single-atom catalysts (SACs) have been extensively investigated as a high-atom-efficiency heterogeneous catalyst for peroxymonosulfate (PMS) oxidation reaction, the stable constructing and activation efficacy of the reaction sites remains less clarified. Herein, we employed gelatin as a N,O-bidentate ligand for Co (II) to form for a N-doped carbon precursor, while introducing NaCl as a template agent to induce the adoption of a Co-N conformation and disorganize the Co-O moiety. This approach facilitates uniform spatial isolation and atomic-level dispersion of Co atoms within the aerogel, effectively inhibiting the aggregation of Co during synthesis and enabling precise and controllable preparation of Co single-atom catalysts (SACs).
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