A Bayesian approach alternative to the one used in the strip-pair comparison method for developing threshold color-difference models is presented in this paper. Strip-pair comparison method is based on the construction of color-control strips made of pairs of patches put in contact and ordered by increasing the CIELAB color difference. Observers are required to indicate the number of the pair of patches in every strip for which they begin to perceive a just noticeable color difference. Frequency data obtained, from repeating several times the visual assessment, is recorded to build a Bayesian multinomial logistic regression model, which allows the determination of the coefficients of the color discrimination ellipsoids. The results of the Bayesian approach agree closely with the results obtained to validate strip-pair comparison method for the same theoretical frequency data. The main advantage of the Bayesian approach over many other methods is that it allows a direct analysis of the statistical variability of the estimated parameters by means of confidence intervals and other measures of statistical variability.
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http://dx.doi.org/10.1364/OE.432157 | DOI Listing |
Front Hum Neurosci
December 2024
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Introduction: As brain-computer interfacing (BCI) systems transition fromassistive technology to more diverse applications, their speed, reliability, and user experience become increasingly important. Dynamic stopping methods enhance BCI system speed by deciding at any moment whether to output a result or wait for more information. Such approach leverages trial variance, allowing good trials to be detected earlier, thereby speeding up the process without significantly compromising accuracy.
View Article and Find Full Text PDFPLoS Genet
December 2024
Laboratory of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Advances in DNA sequencing technology and computation now enable genome-wide scans for natural selection to be conducted on unprecedented scales. By examining patterns of sequence variation among individuals, biologists are identifying genes and variants that affect fitness. Despite this progress, most population genetic methods for characterizing selection assume that variants mutate in a simple manner and at a low rate.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Genetics, National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ), Mexico City, Mexico.
Myelomeningocele (MMC) is the most severe and disabling form of spina bifida with chronic health multisystem complications and social and economic family and health systems burden. In the present study, we aimed to investigate the genetic risk estimate for MMC in a cohort of 203 Mexican nuclear families with discordant siblings for the defect. Utilizing a custom Illumina array, we analyzed 656 single nucleotide polymorphisms (SNPs) of 395 candidate genes to identify a polygenic risk profile for MMC.
View Article and Find Full Text PDFEpidemiology
November 2024
Center for Opioid Epidemiology and Policy, Department of Population Health, NYU Grossman School of Medicine, NY.
Background: Medications for opioid use disorder are associated with lower risk of drug overdoses at the individual level. However, little is known about whether these effects translate to population-level reductions. We investigated whether county-level efforts to increase access to medication for opioid use disorder in 2012-2014 were associated with opioid overdose deaths in New York State during the first years of the synthetic opioid crisis.
View Article and Find Full Text PDFSci Rep
January 2025
Yunnan Diqing Non-Ferrous Metals Co., Ltd, Yunnan, 674400, China.
Fatigue can cause human error, which is the main cause of accidents. In this study, the dynamic fatigue recognition of unmanned electric locomotive operators under high-altitude, cold and low oxygen conditions was studied by combining physiological signals and multi-index information. The characteristic data from the physiological signals (ECG, EMG and EM) of 15 driverless electric locomotive operators were tracked and tested continuously in the field for 2 h, and a dynamic fatigue state evaluation model based on a first-order hidden Markov (HMM) dynamic Bayesian network was established.
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