Happy gut, happy kidneys? Restoration of gut microbiome ameliorates acute and chronic kidney disease.

Cell Metab

Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA; Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY, USA; James J. Peters Veteran Administration Medical Center, New York, NY, USA. Electronic address:

Published: October 2021

In a new study, Zhu et al. (2021) show that mitigating dysbiosis by the probiotic L. casei Zhang reduces kidney inflammation via restoring short-chain fatty acid-producing gut microbiome and nicotinamide metabolism. These findings shed light on the underlying mechanisms of probiotics in treating human kidney diseases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994854PMC
http://dx.doi.org/10.1016/j.cmet.2021.08.019DOI Listing

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