AI Article Synopsis
- Lower oxygen concentrations during anesthetic induction in pediatric patients show less atelectasis right after induction compared to 100% oxygen.
- A study involving 54 children undergoing elective surgeries found that while 60% oxygen resulted in fewer affected lung regions post-induction, there were no significant differences by the end of the surgery.
- The findings suggest that while lower oxygen levels can reduce atelectasis formation initially, this protective effect does not persist throughout the surgery, and 80% oxygen doesn't significantly prevent atelectasis when compared to 100%.
Article Abstract
Background: In adults, the use of lower oxygen concentration during induction is associated with less atelectasis formation without an increase in incidence of hypoxia. However, it is unknown whether this remains true in the pediatric patients.
Methods: Fifty-four pediatric patients who were scheduled to undergo elective lower abdominal surgery were randomized to one of three oxygenation groups: 100%, 80%, or 60% oxygen (in air). During anesthesia induction, patients were ventilated with sevoflurane in 100%, 80%, or 60% oxygen. Endotracheal intubation and mechanical ventilation were performed. Atelectasis was diagnosed using LUS, which was performed after anesthetic induction and at the end of surgery.
Results: We assessed atelectasis after anesthetic induction and at the end of surgery. After anesthetic induction, the number of atelectatic lung regions was significantly different among the three groups (median [IQR], 2.0 [1.0-2.5], 2.0 [1.0-2.8], and 3.0 [2.0-3.0] in the 60%, 80%, and 100% oxygen groups, p = .033) and between the 60% and 100% groups (p = .015), but not between 80% and 100% groups (p = .074). However, no differences in the number of atelectatic lung regions were found among the three groups at the end of surgery (2.0 [1.3-3.8], 3.0 [1.8-3.0], and 4.0 [2.0-4.0] in the 60%, 80%, and 100% oxygen groups; p = .169).
Conclusion: Lower oxygen concentration during anesthetic induction is associated with less atelectasis formation immediately after anesthetic induction in children. In addition, applying 80% oxygen instead of 100% oxygen is not enough to prevent atelectasis formation, and 60% oxygen should be applied to prevent atelectasis. However, this effect does not last until the end of surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/pan.14304 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Difficult airway management in a patient with severe mitral and tricuspid regurgitation, rapid atrial fibrillation, and moderate pulmonary hypertension: a case report.
BMC Anesthesiol
January 2025
Department of Anaesthesiology, West China Hospital, Sichuan University & The Research Units of West China (2018RU012), Chinese Academy of Medical Sciences, Chengdu, 610041, China.
Background: Given the prevalence of cardiovascular disease, encountering difficult airways in this patient population is quite common. The challenge for anesthesiologists lies not only in establishing the airway but also in managing the hemodynamic instability caused by sympathetic activation during intubation. The purpose of this report is to describe the anesthetic experience of this patient with severe mitral and tricuspid regurgitation, atrial fibrillation with rapid ventricular response, and moderate pulmonary hypertension with an anticipated difficult airway.
View Article and Find Full Text PDFApplication value of using a SaCo videolaryngeal mask airway combined with a bronchial blocker in patients undergoing minimally invasive thoracoscopic surgery.
Am J Transl Res
December 2024
Department of Anesthesiology, Xidian Group Hospital Xi'an 710077, Shaanxi, China.
Objective: To investigate the efficacy of the SaCo videolaryngeal mask airway (VLMA) in combination with a bronchial blocker in patients undergoing minimally invasive thoracoscopic surgery.
Methods: A retrospective analysis was conducted on the clinical data of 120 patients who underwent minimally invasive thoracoscopic surgery from January 2022 to December 2023. Patients were grouped based on their treatment methods: 68 patients who received the SaCo VLMA combined with a bronchial blocker intraoperatively were designated as the L group, while 52 patients who received a tracheal tube combined with a bronchial blocker intraoperatively were designated as the E group.
Application of subspecialty standardized temperature management process in a hybrid surgery for acute aortic dissection.
Am J Transl Res
December 2024
Department of Anesthesiology, Huai'an First People's Hospital Huai'an, Jiangsu, China.
Objective: To evaluate the clinical effect of a subspecialty standardized temperature management process in a hybrid surgery for treating acute aortic dissection.
Methods: From January 2020 to June 2021, 102 patients who underwent hybrid surgery for acute aortic dissection in the Department of Cardiovascular Surgery at the Huai'an First People's Hospital were selected as the control group, receiving routine temperature maintenance measures. From August 2021 to November 2022, 105 similar patients from the same hospital were enrolled in the experimental group, where a subspecialty standardized temperature management process was implemented.
Correlation between the Observer's Assessment of Alertness/Sedation score and bispectral index in patients receiving propofol titration during general anesthesia induction.
Nan Fang Yi Ke Da Xue Xue Bao
January 2025
Department of Anesthesiology, Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China.
Objectives: To explore the relationship between the Observer's Assessment of Alertness/Sedation (OAAS) score and the bispectral index (BIS) during propofol titration for general anesthesia induction and analyze the impact of BIS monitoring delay on anesthetic depth assessment.
Methods: This study was conducted among 90 patients (ASA class I-II) undergoing elective surgery under general anesthesia. For anesthesia induction, the patients received propofol titration at the rate of 0.
The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response.
J Pain Res
January 2025
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
Background: Previous research has demonstrated that placebo induction manipulations can reduce an individual's pain through non-specific mechanisms, such as expectancy manipulations. However, despite robust research characterizing these effects, individual differences in predicting placebo analgesic responses are not well understood.
Methods: Fifty-four healthy pain-free adults over 18 (M=22.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!