This paper presents the bidirectional confocal measurement of a microsphere, which enables the simple measurement of the sphere with a similar number of measuring points taken on its upper and its lower hemispheres. The innovative measuring strategy is the placement of the sphere above a mirror and the subsequent measurement of the upper hemisphere on the real sphere and the lower hemisphere on the mirrored sphere. While theoretical explanations are given first, the main focus of the paper is the presentation of the idea itself and the very promising empirical findings. We believe these findings prove that the measuring strategy presented has the potential to become a prime method for the optical characterization of microspheres.
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http://dx.doi.org/10.1364/AO.436355 | DOI Listing |
J Vis Exp
December 2024
Department of Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen;
Foreign body reaction (FBR), an immune-mediated complex healing process, plays a crucial role in integrating implants into the body. Macrophages, as the first line of immune system interaction with implant surfaces, play a bidirectional role in modulating the inflammation-regeneration balance. For a deep understanding and the evaluation of the reactions between implant materials and immune responses, reliable in vitro methods and protocols are pivotal.
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Department of Cardiology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Background: Familial hypercholesterolemia (FH) is a hereditary disease caused mainly by mutations in the gene encoding the low-density lipoprotein receptor (LDLR). This study aimed to confirm the pathogenicity of the LDLR c.97C>T (p.
View Article and Find Full Text PDFJ Imaging
October 2024
College of Automation & Information Engineering, Xi'an University of Technology, Xi'an 710048, China.
J Vis Exp
October 2024
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University;
Mitochondrial transfer is a normal physiological phenomenon that occurs widely among various types of cells. In the study to date, the most important pathway for mitochondrial transport is through tunneling nanotubes (TNTs). There have been many studies reporting that mesenchymal stem cells (MSCs) can transfer mitochondria to other cells by TNTs.
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