A metal-free intramolecular borylative cyclization of 1,6-allenynes driven by BCl was developed. This method provides a general and practical strategy to construct valuable pyrrolidines containing all-carbon quaternary centers or 3,5-dihydroazepine derivatives depending on the substituents of the allene, with conjugative and sterically hindered phenyl groups favoring the latter.
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| http://dx.doi.org/10.1021/acs.orglett.1c03062 | DOI Listing |
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