Purpose: Breast cancer is diagnosed at a median age of 62 years in the USA. At the same time, mortality rates for breast cancer continue to decrease, falling by 40% from 1989 to 2016. In the coming decades, the number of elderly patients with breast cancer, potentially seeking reconstruction, is expected to increase.
Methods: A retrospective chart review of 309 patients, aged 60 years or older, undergoing immediate or delayed breast reconstruction, was conducted. Patient characteristics, clinical information and major complications requiring reoperation were evaluated. Multivariate analyses identified factors contributing to complications such as BMI, comorbidities, smoking status, history of previous breast conservation therapy (BCT), total expander volume, radiotherapy, and chemotherapy.
Results: 26.7% of patients had at least one complication requiring reoperation, and 6.9% of patients suffered reconstructive failure. Logistic regression analysis of all patients (n = 309) found a statistically significant relationship between major complication and history of ipsilateral BCT (p = 0.026) and adjuvant chemotherapy (p = 0.005). Logistic regression analysis in patients undergoing tissue expander (TE) reconstruction (n = 215) showed that major complications were related to BMI over 35 kg/m (p = 0.04), history of ipsilateral BCT (p = 0.048), and adjuvant chemotherapy (p = 0.033).
Conclusion: Breast reconstruction in women over 60 years old was not independently associated with higher major complication rates in our series.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10549-021-06389-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparing synthetic mammograms based on wide-angle digital breast tomosynthesis with digital mammograms.
J Med Imaging (Bellingham)
January 2025
Lund University, Department of Translational Medicine, Medical Radiation Physics, Malmö, Sweden.
Purpose: We aim to investigate the characteristics and evaluate the performance of synthetic mammograms (SMs) based on wide-angle digital breast tomosynthesis (DBT) compared with digital mammography (DM).
Approach: Fifty cases with both synthetic and digital mammograms were selected from the Malmö Breast Tomosynthesis Screening Trial. They were categorized into five groups consisting of normal cases and recalled cases with false-positive and true-positive findings from DM and DBT only.
Comparison of outcomes following prepectoral and subpectoral implants for breast reconstruction in patients with breast cancer.
Front Oncol
January 2025
Thyroid and Breast Medical Center, Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, China.
Background: In recent years, different approaches to implant-based breast reconstruction have increasingly become an important option to meet both the treatment and postoperative aesthetic needs of breast cancer patients. This study selected two commonly used techniques for the prepectoral approach: single-incision, gas-inflated endoscopic prepectoral breast reconstruction (SIE-BR) and open prepectoral implant-based breast reconstruction (C-BR), as well as a commonly used technique for the subpectoral approach: open subpectoral implant-based breast reconstruction (SI-BR). By comparing the clinical efficacy and aesthetic outcomes of these three techniques in the treatment of breast cancer patients, this study aims to summarize the advantages of the prepectoral approach.
View Article and Find Full Text PDFA Threshold Technique Study to Understand Patient Preference for Smooth Versus Textured Breast Implants.
Plast Reconstr Surg Glob Open
January 2025
U.S. Food and Drug Administration (FDA), Center for Devices and Radiological Health, Silver Spring, MD.
Background: Breast implant surfaces are categorized as smooth or textured. Compared with smooth implants, textured surface implants have a higher risk of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) but may have a lower risk of capsular contracture (CC). This study aimed to quantify whether survey respondents would be willing to accept a higher risk of BIA-ALCL in exchange for the potential reported benefits of textured breast implants.
View Article and Find Full Text PDFEvidence-based Algorithms for Free Deep Inferior Epigastric Perforator Flap Salvage in Autologous Breast Reconstruction.
Plast Reconstr Surg Glob Open
January 2025
Division of Plastic, Reconstructive and Aesthetic Surgery, University of Toronto, Toronto, ON, Canada.
Background: Breast reconstruction with the deep inferior epigastric perforator (DIEP) free flap has become the gold standard for autologous breast reconstruction. Flap take-back to the operating room (OR) is an uncommon but difficult situation, requiring prompt and accessible resources. We conducted a literature review and independent expert review to inform evidence-based perioperative algorithms in the event of DIEP flap compromise.
View Article and Find Full Text PDFSurgical Management of Gestational Gigantomastia: A Case Report Highlighting Therapeutic Intervention.
Plast Reconstr Surg Glob Open
January 2025
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Gigantomastia is an exceedingly rare condition characterized by extraordinary growth of breasts during pregnancy, and its underlying etiology remains elusive. Although surgical intervention is the primary treatment modality, there have been emerging prospects for utilizing adjunctive medical therapies, such as bromocriptine, to address this challenging condition. Herein, we report the case of a 26-year-old woman who experienced abrupt and asymmetric bilateral breast enlargement commencing in the second month of her pregnancy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!