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Bloodstream Infection Combined with Thoracic Infection Caused by : A Case Report and Review of the Literature.
Infect Drug Resist
December 2024
Department of Laboratory Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, People's Republic of China.
Objective: is usually found in urogenital tract infections and is associated with several extra-genitourinary infections, including septic arthritis, bacteremia, and meningitis. Here, we report a rare case of induced bloodstream infection with thoracic inflammation in a surgical patient.
Methods: A 56-year-old male who underwent surgery for multiple pelvic and rib fractures developed fever, pleural effusion, and wound exudation despite receiving prophylactic anti-infection treatment with cefotiam.
γ-Cyclodextrin hydrogel for the sustained release of josamycin for potential ocular application.
Drug Deliv
December 2024
Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany.
Glaucoma is the leading cause of blindness worldwide. However, its surgical treatment, in particular via trabeculectomy, can be complicated by fibrosis. In current clinical practice, application of the drug, Mitomycin C, prevents or delays fibrosis, but can lead to additional side effects, such as bleb leakage and hypotony.
View Article and Find Full Text PDFDirect comparison of anti-inflammatory effects of 14-, 15-, and 16-membered macrolide antibiotics in experimental inflammation model induced by carrageenan in rats.
Pharmazie
May 2024
Division of Pharmacodynamics, Keio University Faculty of Pharmacy, Tokyo, Japan; Division of Practical Pharmacy, Keio University Faculty of Pharmacy.
Some macrolide antibiotics, which share a basic lactone ring structure, also exhibit anti-inflammatory actions in addition to their antibacterial activities. However, no study has directly compared anti-inflammatory effects on acute inflammation among macrolide antibiotics with the distinct size of the lactone ring. In this study, we evaluated and compared the anti-inflammatory activities of four 14-membered macrolides (erythromycin, clarithromycin, roxithromycin, oleandomycin), one 15-membered macrolide (azithromycin), and three 16-membered macrolides (midecamycin, josamycin, leucomycin) using a rat carrageenan-induced footpad edema model.
View Article and Find Full Text PDFAntimicrobial resistance of genital mycoplasmas recovered from nonpregnant women in Greece: trends over the last 15 years.
Future Microbiol
July 2024
Department of Biopathology, Aretaieion University Hospital, Medical School, National & Kapodistrian University of Athens, 76 Vasilisis Sofias Avenue, Athens, 11528, Greece.
To study antimicrobial susceptibilities of genital mycoplasmas recovered from endocervical samples of reproductive-age, nonpregnant women ( = 8,336). For isolation and susceptibility testing, the Mycoplasma IST2 kit was used. As many as 2093 samples were positive for mycoplasmas.
View Article and Find Full Text PDFBackground: Ureaplasma urealyticum (U. urealyticum) commonly occurs in female genitourinary infections, and its different biovars and serotypes have varying degrees of resistance to different antibiotics. This study aimed to ex-plore the characteristics of U.
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