Risk factors for rebleeding in patients with obscure gastrointestinal bleeding from southern China.

J Int Med Res

Research Experimental Center, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, P. R. China.

Published: October 2021

Background: To identify the risk factors associated with rebleeding in obscure gastrointestinal bleeding (OGIB) patients from southern China.

Methods: This retrospective study involved 229 patients who underwent small bowel endoscopy in our hospital between 1 January 2018 and 1 December 2020. The clinical characteristics and risk factors related to rebleeding were retrospectively evaluated.

Results: Rebleeding patients were significantly older than non-rebleeding patients (53.0 ± 15.9 46.2 ± 17.8 years), had lower hemoglobin concentrations (89.2 ± 28.1 126.2 ± 25.1 g/L), and higher blood urea nitrogen concentrations (5.4 ± 2.6 4.5 ± 2.2 µmol/L), respectively. A higher percentage of rebleeding patients had diabetes mellitus (13.9% 2.9%) and overt bleeding (70.4% 38.6%), and required blood transfusions (43.1% 8.0%), compared with non-rebleeding patients, respectively. Multivariate logistic analysis indicated that drinking alcohol (odds ratio (OR): 9.27; 95% confidence interval (CI) = 1.35-63.78), anemia (OR: 17.38; 95% CI = 5.48-55.10), and blood transfusion (OR: 3.76; 95% CI = 1.04-13.56) increased the risk of rebleeding in OGIB patients.

Conclusion: Our data suggested that OGIB patients who drink alcohol, have anemia, and require blood transfusion have an increased risk of rebleeding.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493185PMC
http://dx.doi.org/10.1177/03000605211028422DOI Listing

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