Our case report includes a 42 year old male who had C6-C7 fracture dislocation with complete spinal cord injury following a motor vehicle accident. The patient underwent combined anterior and posterior fixation of the cervical spine. However, the patient had hypotension as a part of neurogenic shock and required vasopressor to maintain mean arterial pressure. The patient was treated in Intensive Care Unit with noradrenaline infusion to maintain mean arterial pressure but it was really challenging to stop the vasopressor. The patient was started on oral Midodrine and Fludrocortisone; vasopressor dose was tapered and finally stopped.
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http://dx.doi.org/10.1016/j.amsu.2021.102811 | DOI Listing |
Clin Auton Res
December 2024
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Aim: The study aimed to assess the haemodynamic effects of fludrocortisone and midodrine, alone or combined, in patients with recurrent syncope and/or symptoms due to hypotension and ≥ 1 daytime systolic blood pressure (SBP) drop < 90 mmHg or ≥ 2 daytime SBP drops < 100 mmHg recorded by 24-h ambulatory blood pressure monitoring (ABPM1).
Method: A total of 53 patients (mean age, 40.9 ± 18.
Purpose: Orthostatic hypotension (OH) is a common manifestation of Parkinson's disease (PD). Factors including autonomic dysfunction from the disease, use of PD medications, comorbidities, and aging can contribute to an increased risk of OH, which can be detrimental to patients' quality of life. Maintaining a fine balance to prevent harm related to OH and retain the benefit medications used to treat PD is crucial.
View Article and Find Full Text PDFCardiovasc Endocrinol Metab
December 2024
Nephrology Department, Garden City Hospital, Michigan State University, Garden City.
Diabetic autonomic neuropathy (DAN) and its associated cardiovascular autonomic neuropathy (CAN) can lead to potentially fatal complications. We analyzed two distinct cases of DAN/CAN based on comprehensive cardiovascular autonomic reflex tests (CARTs). Case 1 involves a 27-year-old patient with T1DM suffering from recurrent severe hypoglycemic unawareness due to DAN.
View Article and Find Full Text PDFJ Pediatr Pharmacol Ther
October 2024
Department of Pharmacy (TMA), Le Bonheur Children's Hospital, Memphis TN.
Postural orthostatic tachycardia syndrome (POTS) is a chronic illness with unknown mortality and high morbidity, often diagnosed in the adolescent years. Published literature regarding POTS primarily focuses on the adult population, and guidance on treatment in pediatrics is sparse. The purpose of this clinical review is to evaluate the current literature on the management of POTS in pediatric patients.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
July 2024
Department of Medicine, St. Luke's Hospital, Monroe, PA, USA.
Endocrinopathies following immunotherapy have infrequently been documented in the literature. Adrenal insufficiency is a rare consequence of pembrolizumab immunotherapy, with incidence reported to be between 0.98 and 1.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!