Objective: To compare the shear wave elastography (SWE) values of perineal tissues in female patients with stress urinary incontinence and those without incontinence.
Study Design: Prospective case control study.
Place And Duration Of Study: University of Health Sciences, Adana City Training and Research Hospital, Adana, Turkey from March 2019 to March 2020.
Methodology: Seventy women with stress urinary incontinence ranging between 40-70 years; and 30 women of similar age and weight without complaints of incontinence were selected as cases and control group, respectively. SWE values of the external urethral sphincter, bladder neck, mid-urethral and pubococcygeal muscle regions were measured dynamically, both at rest and during Valsalva manoeuver by transperineal ultrasonography. Moreover, the medial pubic symphysis of the participants was taken as a fixed point and the angle between the bladder neck and urethra was measured at rest and during Valsalva. Patients with incontinence were divided into groups, mild and severe, according to the bladder stress test results.
Results: The angle change was statistically significantly higher in the severe and mild groups than the control group (p <0.001). There was no statistically significant difference between the bladder neck region elastography values in Valsalva manoeuver between the control group and the mild group, but the difference in the severe group was statistically significantly lower (p = 0.005). No statistically significant difference was found between the control group and the mild group in terms of the mid-urethral region values at rest, but the difference in the severe group was statistically significantly lower (p ˂0.001).
Conclusion: SWE is a promising new imaging method in the evaluation of urethral hypermobility in stress urinary incontinence. Key Words: Ultrasonography, Shear wave elastography, Stress urinary incontinence, Transperineal ultrasonography.
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http://dx.doi.org/10.29271/jcpsp.2021.10.1196 | DOI Listing |
Low Urin Tract Symptoms
January 2025
Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Aim: This study aimed to analyze the clinical efficacy and safety of autologous fascial pubovaginal sling (AFPVS) surgery in treating recurrent stress urinary incontinence (SUI) following the failure of mid-urethral sling procedures.
Methods: A retrospective analysis was conducted on the clinical data of SUI patients who underwent AFPVS at our hospital between 2008 June and 2024 June following the failure of mid-urethral sling procedures. The analysis included basic information, surgical parameters, and postoperative complications.
Sci Rep
January 2025
Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University Bratislava, SK-83232, Bratislava, Slovakia.
Oxidative stress and apoptosis are highly engaged in development of diabetic nephropathy (DN). In monotherapy, dapagliflozin and pioglitazone positively modulate target organ damage even independently of their hypoglycaemic effect. This study evaluated whether a simultaneous PPARγ activation and SGLT cotransporter inhibition offer superior protection against DN-related oxidative and apoptotic processes in a T1DM rat model.
View Article and Find Full Text PDFLow Urin Tract Symptoms
January 2025
Farwaniya Hospital, Farwaniya, Kuwait.
Objectives: During holmium laser enucleation of the prostate (HOLEP), blunt dissection (BD) by pushing the tip of the scope may exert mechanical force on the sphincter that could be avoided by adopting laser dissection (LD). This study evaluates the continence recovery in consecutive patients who underwent BD and LD.
Methods: A prospective cohort of patients who underwent LD was compared with a retrospective control that underwent BD.
Alzheimers Dement
December 2024
Imperial College London, London, United Kingdom; UK Dementia Research Institute, Care Research and Technology Centre, London, United Kingdom.
Background: Close to 23% of unplanned hospital admissions for people living with dementia (PLWD) are due to potentially preventable causes such as severe urinary tract infections (UTIs), falls, and respiratory problems. These affect the well-being of PLWD, cause stress to carers and increase pressure on healthcare services.
Method: We use routinely collected in-home sensory data to monitor nocturnal activity and sleep data.
Sheng Li Xue Bao
December 2024
Health Science Center, East China Normal University, Shanghai 200241, China.
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal function. Renal ischemia-reperfusion injury (RIRI) is one of the main causes of AKI with the underlying mechanism incompletely clarified. The liver X receptors (LXRs), including LXRα and LXRβ, are members of the nuclear receptor superfamily.
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