AI Article Synopsis
- Laparoscopic liver resection (LLR) is considered a safe option for treating hepatocellular carcinoma (HCC), though repeat surgeries are often needed, and the role of minimally invasive liver surgery (MILS) is still being clarified.
- This study, involving data from 52 medical centers and 1054 patients, aims to compare outcomes between first-time LLR and repeat LLR while also looking at the difference between primary open surgery and MILS.
- After matching the groups, the results showed no significant differences in outcomes between first and repeat LLR or between the open and MILS approaches, indicating that MILS is a feasible and safe option for repeat liver resections.
Article Abstract
Laparoscopic liver resection (LLR) for Hepatocellular carcinoma (HCC) is a safe procedure. Repeat surgery is more often required, and the role of minimally invasive liver surgery (MILS) is not yet clearly defined. The present study analyzes data compiled by the Italian Group of Minimally Invasive Liver Surgery (IGoMILS) on LLR. To compare repeated LLR with the first LLR for HCC is the primary endpoint. The secondary endpoint was to evaluate the outcome of repeat LLR in the case of primary open versus primary MILS surgery. The data cohort is divided into two groups. Group 1: first liver resection and Group 2: Repeat LLR. To compare the two groups a 3:1 Propensity Score Matching is performed to analyze open versus MILS primary resection. Fifty-two centers were involved in the present study, and 1054 patients were enrolled. 80 patients underwent to a repeat LLR. The type of resection was different, with more major resections in the group 1 before matching the two groups. After propensity score matching 3:1, each group consisted of 222 and 74 patients. No difference between the two groups was observed. In the subgroup analysis, in 44 patients the first resection was performed by an open approach. The other 36 patients were resected with a MILS approach. We found no difference between these two subgroups of patients. The present study in repeat MILS for HCC using the IGoMILS Registry has observed the feasibility and safety of the MILS procedure.
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| http://dx.doi.org/10.1007/s13304-021-01161-w | DOI Listing |
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