Background: Erectile dysfunction is a distressing complication of diabetes among male patients. Despite being a serious concern affecting sexual health, the issue regarding sexual dysfunction is seldom discussed by patients with physicians in developing countries. This study aimed to identify the prevalence of Erectile dysfunction and its association with other risk factors among type 2 Diabetic males attending the tertiary care hospital in Nepal.
Methods: A cross-sectional hospital-based study was carried out in the Diabetes Out Patient Department of Tribhuvan University Teaching Hospital, Kathmandu, Nepal. 160 male patients with a history of Type 2 Diabetes Mellitus (T2DM) meeting the inclusion criteria were enrolled in the study with informed consent. A validated questionnaire; an abridge 5 item version of the International Index of Erectile Function (IIEF 5) was used to assess the erectile function where the score below 22 was considered as having erectile dysfunction. The severity of erectile dysfunction was categorized based on IIEF 5 score.
Results: The prevalence of erectile dysfunction with varying degrees of severity was found to be 76.87% among T2DM male patients. There was a significant negative correlation of the IIEF5 Score with the duration of T2DM burden (r= -0.416, p<0.05) and the level of HbA1c (r= -0.391, p<0.05).
Conclusions: There was a higher prevalence of erectile dysfunction among T2DM male patients that were also associated with poor glycemic control and the duration of T2DM burden.
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http://dx.doi.org/10.33314/jnhrc.v19i2.3394 | DOI Listing |
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
January 2025
Shanxi Key Laboratory of Food and Drug Safety Prevention and Control, Inspection and Testing Center of Shanxi Province, Taiyuan, Shanxi, China.
Two novel phosphodiesterase 5 (PDE-5) inhibitors were detected in pressed candy using high-performance liquid chromatography (HPLC)-diode array detection. Following extraction with acetonitrile and sonication, the compounds were isolated and purified semi-preparative liquid chromatography. Structural characterisation was achieved through high-resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR) spectroscopy.
View Article and Find Full Text PDF3D Print Med
January 2025
Department of Surgical & Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Background: Penile implant surgery is the standard surgical treatment for end-stage erectile dysfunction. However, the growing complexity of modern high-tech penile prostheses has increased the demand for more practical training opportunities. The most advanced contemporary training methods involve simulation training using cadavers, with costs exceeding $5,000 per cadaver, inclusive of biohazard fees.
View Article and Find Full Text PDFPrz Gastroenterol
August 2023
Department of Physical Therapy for Internal Medicine and Geriatrics, Faculty of Physical Therapy, October University for Modern Sciences and Arts, 6th October City, Egypt.
Introduction: Exercise is a simple, safe, and affordable solution that can be easily taught to men with chronic illnesses to improve their psychological burden and sexual health.
Aim: Since the role of exercise in ameliorating the psychological burden associated with erectile dysfunction (ED) in hepatitis C (HC) men was not explored, this research aimed to explore this role.
Material And Methods: This HC study was a randomized-controlled exercise-rehabilitation trial.
Sex Med
December 2024
Department of Urology, Xiangya Hospital, Central South University, Changsha 410000, China.
Background: While previous studies have explored the associations and causalities among platelet count (PC), mean platelet volume (MPV), and erectile dysfunction (ED), further investigations are needed to clarify these relationships using advanced methodologies and analyzing specific populations.
Aim: To investigate the associations and causalities among PC, MPV, and ED using observational study and Mendelian randomization (MR) analysis.
Methods: A total of 114 patients with ED and 158 healthy control participants underwent a fasting blood draw to test for PC and MPV along with a comprehensive laboratory examination.
Sex Med
December 2024
Visiting staff, Division of Urology, Department of Surgery, Yuan's General Hospital, Kaohsiung City 802793, Taiwan, Republic of China.
Background: Both serum testosterone (T) levels and erectile dysfunction (ED) are associated with systemic diseases in men and ED is the most common presenting symptom of hypogonadism.
Aim: To evaluate the association of serum total testosterone (TT) levels with cardiometabolic diseases in men with ED.
Methods: Serum endogenous TT levels were determined to evaluate their associations with cardiometabolic diseases in men with ED in outpatient clinics.
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