Introduction: There is some evidence regarding the role of LAG-3, TLR mediated neuroinflammation in PD.

Methods: sLAG-3, TOLLIP, NLRP3 levels were measured in PD and healthy controls.

Results: These markers were significantly higher in PD and were associated with progression.

Conclusion: sLAG3 and TOLLIP are involved in the NLRP3 mediated inflammatory activation in PD.

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http://dx.doi.org/10.1016/j.parkreldis.2021.09.019DOI Listing

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