AI Article Synopsis

  • Black people in the U.S. have higher rates and severity of atopic dermatitis (AD) compared to White people, while the Latinx population shows less researched but notable differences in AD characteristics.
  • Genetic factors linked to AD risk appear less prevalent among Black individuals, suggesting that social and environmental issues may play a larger role in these disparities.
  • Emphasizing socioeconomic, environmental, and healthcare factors influenced by racism is crucial to understanding and addressing the differences in AD prevalence and severity among racial and ethnic groups, rather than focusing solely on genetic explanations.

Article Abstract

Black people in the United States experience greater atopic dermatitis (AD) prevalence, severity, and persistence when compared with White people. Although very little published literature describes AD in the Latinx population, additional differences in severity, persistence, and age of onset exist in contrast to White people. Thus far, genetic polymorphisms associated with increased risk and/or severity of AD are less common among Black people, so should confer reduced, rather than the observed increased, AD risk among Black people. Little is known regarding genetic risk factors in Latinx people. In contrast, there is consistent evidence that socioeconomic, environmental, and health care factors influence AD prevalence, severity, and/or persistence, and these same risk factors are more common among racial and ethnic minority populations as a result of racism. Researchers too often pursue genetic explanations for racial and ethnic AD disparities when the evidence points to the importance of contextual, rather than genetic, causes of these disparities. Reframing the prevailing view that innate differences among racial and ethnic groups are responsible for these disparities by emphasizing the role of racism and its downstream effects on contextual factors will be a critical first step toward shrinking these disparities.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578465PMC
http://dx.doi.org/10.1016/j.jaci.2021.09.015DOI Listing

Publication Analysis

Top Keywords

racial ethnic
16
black people
12
ethnic disparities
8
atopic dermatitis
8
prevalence severity
8
severity persistence
8
white people
8
people genetic
8
increased risk
8
risk factors
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!