Purpose: Evaluation of the patency and position of perforated lacrimal punctal plugs implanted for treating punctal stenosis together with quantitative assessment of the precorneal tear film using anterior segment optical coherence tomography (AS-OCT).
Methods: In a prospective study, the lower punctum of 54 eyes of 29 patients implanted with perforated punctal plugs were examined using AS-OCT during the early postoperative period. Preoperative tear meniscus height (TMH) and tear meniscus area (TMA) were evaluated. Postoperatively, the patency of the plug, its position, TMH and TMA were evaluated, and the results were correlated with postoperative epiphora. Munk scale was used for epiphora grading.
Results: Using AS-OCT, 48 (88.9%) plugs were found in proper position while 6 (11.1%) were rotated. The lumen of the plugs was completely patent in 47 (87%) plugs, partially obstructed in 2 (3.7%) plugs and completely occluded in 5 (9.2%) plugs. There was a statistically significant postoperative decrease of TMH and TMA (P < 0.001) and postoperative epiphora Munk score (P < 0.001).
Conclusion: AS-OCT is a valuable, reliable, and noninvasive investigative tool that can detect the proper positioning, patency, and contents of the implanted perforated lacrimal punctal plugs in addition to measurement of TMH and TMA. Trial registration ClinicalTrials.gov ID: NCT04624022, https://clinicaltrials.gov/ct2/show/NCT04624022.
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http://dx.doi.org/10.1186/s40662-021-00259-x | DOI Listing |
Ocul Surf
December 2024
Department of Prof. Gabison, A. De Rothschild Foundation Hospital, Paris, France. Electronic address:
Purpose: Graft-versus-host disease (GVHD) is a common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). GVHD may affect several organs, including ocular manifestations, ranging from dry eye syndrome to sight-threatening corneal ulceration or perforation. Limited information is available about characteristics and treatments of ocular GVHD and its relation to general prognosis.
View Article and Find Full Text PDFMedicina (Kaunas)
October 2024
Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki City 852-8501, Japan.
: Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disorder characterized by the formation of intranuclear inclusions in cells. Adult-type NIID usually develops in elderly patients with various clinical manifestations and is sometimes accompanied by ocular symptoms. A case of adult-onset NIID with early and unique manifestations, including a progressive corneal defect and retinal changes, which are concerning at a young age, is reported.
View Article and Find Full Text PDFEye Contact Lens
November 2024
Department of Ophthalmology (J.J.M., N.E., W.C.F., A.M.F.), University of North Carolina, Chapel Hill, NC; Department of Ophthalmology (J.J.M.), University of Auckland, Auckland, New Zealand; Tricore Reference Laboratories (K.C.), Albuquerque, NM; Brooke Army Medical Center (E.A.), San Antonio, TX; Medical College of Wisconsin Department of Ophthalmology (N.E.), Milwaukee, WI; Campbell University School of Medicine (W.C.F.), Lillington, NC; Department of Pathology-Laboratory Medicine (P.G.), University of North Carolina School of Medicine, Chapel Hill, NC; and Department of Ophthalmology (A.M.F.), Duke University, Durham, NC.
Eye (Lond)
October 2024
Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Curr Eye Res
October 2024
Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China.
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