The widespread use of antibiotics has raised global concerns, but scarce information on antibiotics in the subtropical marine environment is available. In the present study, seawater and sediment samples were collected to investigate the occurrence, spatial distribution, source, and ecological risks of 22 antibiotics in the Beibu Gulf. The total concentrations of target antibiotics (∑antibiotics) were in the range of 1.74 ng/L to 23.83 ng/L for seawater and 1.33 ng/g to 8.55 ng/g dry weight (dw) for sediment. Spatially, a decreasing trend of antibiotic levels from coast to offshore area was observed, with relatively high levels at the sites close to the Qinzhou Bay and Qiongzhou Strait. Sulfamethoxazole (SMX), trimethoprim (TMP), and norfloxacin (NOX) were predominant in seawater, while NOX, enoxacin (ENX), and enrofloxacin (ENR) were the most abundant antibiotics in sediment. In general, the sediment-water partitioning coefficients (K) were positively correlated with log molecular weight (MW). Salinity, particle size, and pH of water were predicted to be vital factors influencing the partition of sulfadiazine (SDZ), CIX, and ENR (p < 0.05). Livestock and aquaculture were identified as dominant sources of antibiotics in the Beibu Gulf based on PCA-MLR and Unmix model. Risk assessment revealed that SMX, CIX could pose medium risks to algae in the Beibu Gulf. Overall, our results provided paramount insights into understanding the fate and transport behaviors of antibiotics in the subtropical marine environment.
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http://dx.doi.org/10.1016/j.scitotenv.2021.150439 | DOI Listing |
J Hazard Mater
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School of Chemistry and Environment, Guangdong Provincial Observation and Research Station for Tropical Ocean Environment in Western Coastal Water, Guangdong Ocean University, Zhanjiang 524088, China.
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Laboratory for Marine Science and Technology, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China.
China has recently launched extensive marine ranching projects, highlighting the need for scientific evaluation of ecosystem structure and function to guide their development. This study established two energy flow models and an evaluation index system to assess the structure, function, carrying capacity, and ecological status of both a marine ranching ecosystem and a nearby control site in the Beibu Gulf. The results show that the ranching ecosystem outperformed the control ecosystem in terms of food chain length, system size, and ecological carrying capacity of economically important species.
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Sanya Institute of Breeding and Multiplication, School of Marine Biology and Fisheries, Collaborative Innovation Center of Marine Science and Technology, Hainan University, China; Engineering Research Center of Hainan Province for Blue Carbonand Coastal Wetland Conservation and Restoration, China; International Joint Research Center of Hainan Province for Blue Carbon and Coastal Wetland, China. Electronic address:
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School of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, P. R. China.
Macrocyclic supramolecular materials play an important role in encapsulating anticancer drugs to improve the anticancer efficiency and reduce the toxicity to normal tissues through host-guest interactions. Among them, pillar[n]arenes, as an emerging class of supramolecular macrocyclic compounds, have attracted increasing attention in drug delivery and drug-controlled release due to their high biocompatibility, excellent host-guest chemistry, and simplicity of modification. In this review, we summarize the research progress of pillar[n]arene-based supramolecular nanodrug delivery systems (SNDs) in recent years in the field of tumor therapy, including drug-controlled release, imaging diagnostics and therapeutic modalities.
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Sanya Institute of Breeding and Multiplication, School of Marine Biology and Fisheries, Collaborative Innovation Center of Marine Science and Technology, Hainan University, Hainan, China; Engineering Research Center of Hainan Province for Blue Carbon and Coastal Wetland Conservation·and·Restoration, China; International Joint Research Center of Hainan Province for Blue Carbon and Coastal Wetland, China. Electronic address:
Vibrio harveyi is a common sort of pathogenic bacterium in marine, which annually gives rise to huge financial losses in aquaculture industry. Flagellin is one of the important virulence factors for bacteria, but meanwhile it is also a preferable vaccine candidate. In this study, we have identified and analyzed two flagellin antigens of V.
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