Cases of Multiple sclerosis are being increasingly recognized in Sri Lanka and South Asia challenging the concept of MS being a disease of the West. Our study estimates a crude prevalence of 7.78 cases per 100,000 population in Sri Lanka. They carry a secure diagnosis satisfying the 2017 McDonalds criteria with sero-negativity for AQP4 and MOG antibodies. Demography and clinical presentations are similar to the western and regional nations. They show excellent visual and mobility outcomes over a long period of follow up. Further studies are necessary to evaluate a possible genetic predisposition contributing to the benign disease course.

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http://dx.doi.org/10.1016/j.msard.2021.103276DOI Listing

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