[Improving Quality of Life in Patients with Refractory Schizophrenia After Virtual Reality-assisted Therapy: A Content Analysis].

Objectives Schizophrenia, particularly treatment-resistant schizophrenia (TRS), is one of the most disabling psychiatric disorders in terms of adverse effects on the quality of life (QOL) of patients. Subjective QOL has become a particularly crucial target that should be improved with treatment, since improved QOL may lead to recovery in patients with schizophrenia. However, there is little evidence on the efficacy of recommended psychosocial interventions on non-symptomatic measures such as QOL. In this regard, the treatment of schizophrenia can be enhanced if, in addition to the treatment of symptoms, therapeutic emphasis is placed on other areas of importance to patients. With advancements in technology, Virtual Reality assisted Therapy (VRT) allows voice hearers to enter in a direct dialogue with an avatar, fully animated by the therapist, who represents their most persecuting voice. This is in the aim to allow them to gain better control over their voices and to work on their self-esteem. Beyond symptomatology, the results of the pilot projects on this innovative therapy have shown significant results on QOL. Method To refine the observed quantitative results, this article will explore emerging themes from a content analysis arising from the spontaneous discourse of 10 patients who responded well to TRV. Results Four general themes emerged: (i) impact of therapy on voices, (ii) interpersonal relationships, (iii) psychological well-being, and (iv) lifestyle. This content analysis has identified several spheres of life that are further improved in patients with TRS using TRV. Conclusion TRV highlights the future of patient-oriented approaches that integrate several relevant processes to potentially improve QOL. TRV can have potentially immense implications for the health and quality of life of patients. This study was a first step towards exploring the subjective effects of TRV on the lives of patients beyond the symptoms.