AI Article Synopsis

  • The effectiveness of adjunctive corticosteroids in managing viral central nervous system (CNS) infections is not well understood, leading to confusion among clinicians about their use.
  • Limited research exists on how steroids might help in these cases, making it challenging to determine their true benefits.
  • The text explores steroid administration in three specific viral CNS diseases: varicella zoster virus (VZV), Powassan virus, and influenza A-linked acute necrotizing encephalopathy.

Article Abstract

The role of adjunctive corticosteroids in reducing morbidity and mortality of viral CNS infections remains poorly defined. Clinicians are often left in a quagmire regarding steroid use in complex and rapidly evolving viral CNS infections. Limited studies have explored the underlying mechanisms behind the potential benefit of steroids. Here, we describe steroid use in three cases of viral CNS disease: varicella zoster virus (VZV), Powassan virus, and influenza A-associated acute necrotizing encephalopathy.

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Source
http://dx.doi.org/10.1007/s13365-021-01008-5DOI Listing

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