AI Article Synopsis
- COVID-19 primarily causes respiratory symptoms, but a small number of children can develop Multisystem Inflammatory Syndrome (MIS-C) after infection, which can lead to neurological issues.
- A case was reported of a child with MIS-C who experienced cerebellar lesions and encephalopathy, showing worsening neurological symptoms like ataxia and dysarthria during the illness.
- This case is significant as it is the first documented instance of a child with MIS-C developing cerebellar lesions on MRI, indicating possible cerebellitis.
Article Abstract
Background: Coronavirus disease-2019 (COVID-19) is characterized predominantly by respiratory symptoms and has affected a small subset of children. Multisystem inflammatory syndrome in children (MIS-C) has been reported in children following COVID-19. There is increasing report that COVID-19 may also lead to neurologic manifestations. Cerebellar lesions may be observed in viral infections.
Case Report: We report a child with MIS-C related to severe acute respiratory syndrome coronavirus 2, who developed cerebellar lesion during the disease course. Encephalopathy was the first central nervous system symptom. His consciousness improved but he developed clinical signs of cerebellar dysfunction including ataxia, dysarthria and nystagmus. Brain magnetic resonance imaging (MRI) revealed symmetrical pathological signal changes in both cerebellar hemispheres.
Conclusion: We demonstrated the first child with MIS-C to develop cerebellar lesion on brain MRI, suggestive of cerebellitis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658064 | PMC |
| http://dx.doi.org/10.1097/INF.0000000000003358 | DOI Listing |
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