Chronic thoracic pain and chronic abdominal pain are common conditions that can significantly affect quality of life. Pain syndromes encompassing a variety of causes, including cancer pain, neuritis, and postsurgical pain, are traditionally managed by the use of pharmacologic therapy; however, many cases are refractory to these conservative methods. Radiofrequency ablation (RFA) has been increasingly used as a tool to treat resistant, chronic pain of both thoracic and abdominal origin. Multiple cases and trials have been reported that show the efficacy of RFA in the treatment of these chronic pain conditions.
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http://dx.doi.org/10.1016/j.pmr.2021.05.004 | DOI Listing |
Sensors (Basel)
December 2024
Department of Nursing, Physiotherapy and Medicine, University of Almería, La Cañada de San Urbano, 04120 Almería, Spain.
Background: Non-specific chronic neck pain is a prevalent musculoskeletal disorder with a significant impact on individuals' quality of life. The lack of consensus on effective therapeutic management complicates the establishment of standardized treatment protocols. Home exercise programs have yielded positive results.
View Article and Find Full Text PDFPharmaceutics
December 2024
Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, 412 E Spokane Falls Blvd., Spokane, WA 99202, USA.
Morphine is a commonly prescribed opioid analgesic used to treat chronic pain. Morphine undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7 to form morphine-3-glucuronide and morphine-6-glucuronide. Morphine is the gold standard for chronic pain management and has a narrow therapeutic index.
View Article and Find Full Text PDFPharmaceutics
November 2024
Division of Pharmacy, School of Allied Health, The University of Western Australia, Perth, WA 6009, Australia.
: Medicine acceptability is crucial for paediatric drug development, yet its assessment remains challenging due to the multifaceted nature of sensory attributes like taste, smell, and mouthfeel. Traditional methods of acceptability evaluation often involve complex questionnaires and lack standardisation, leading to difficulties in a comparative analysis across studies. This study aimed to develop a simplified, standardised approach for assessing medicine acceptability introducing the Net Promoter Score (NPS) framework to derive a Medicine Acceptability Score (MAS).
View Article and Find Full Text PDFToxics
December 2024
Medical Center for Neck and Low Back Pain, Xijing Hospital, Fourth Military Medical University, Xi'an 710000, China.
This study investigates the correlation between short-term exposure to nitrogen dioxide (NO) and hospitalization for chronic kidney disease (CKD) in Lanzhou, China. A distributed lag nonlinear model (DLNM) was employed to examine the relationship between changes in NO concentration and CKD hospitalizations. Subgroup analyses were conducted to assess the sensitivity of different populations to NO exposure.
View Article and Find Full Text PDFNutrients
December 2024
Department of Biochemistry, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Background: Osteoarthritis (OA) is a chronic condition characterized by joint pain and disability, driven by excessive oxidative stress and inflammatory cytokine production in chondrocytes, resulting in cell death and cartilage matrix breakdown. Our previous study showed that in monosodium iodoacetate (MIA)-induced OA rats, oral administration of heat-killed subsp. 557 (LDL557) could significantly decrease OA progression.
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