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Three new polyketide derivatives of the endophytic fungus 2H1. | LitMetric

Three new polyketide derivatives of the endophytic fungus 2H1.

J Asian Nat Prod Res

State Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.

Published: August 2022

Three new polyketide derivatives, 2-ethoxycarbonyl-endocrocin (), 6-methoxy-2-ethoxycarbonyl-endocrocin () and pannorin C (), along with sixteen known compounds () were isolated from a plant endophytic fungus 2H1. Their structures were elucidated by 1D/2D NMR and HR-ESI-MS data analysis. Compound showed weak antibacterial activity against (MIC 20 μg/ml). Compounds and showed effective cytotoxicity on human melanoma A375 cells (IC 4.13 μM for , 3.39 μM for ).

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http://dx.doi.org/10.1080/10286020.2021.1972982DOI Listing

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